Frequent RNF43 mutation contributes to moderate activation of Wnt signaling in colorectal signet-ring cell carcinoma

Yaqi Li; Jian Li; Renjie Wang; Long Zhang; Guoxiang Fu; Xueying Wang; Yebin Wang; Chuantao Fang; Dandan Zhang; Duo Du; Xiaoji Ma; Mengxue Pan; Qiang Guo; Xiaoya Xu; Xiang Hu; Yi Zhou; Shaobo Mo; Huijun Wang; Jianjun Gao; Shenglin Huang; Yun Liu; Sanjun Cai; Guoqiang Hua; Junjie Peng; Fa-Xing Yu

doi:10.1007/s13238-020-00691-0

Protein Cell ›› 2020, Vol. 11 ›› Issue (4) : 292 -298. DOI: 10.1007/s13238-020-00691-0

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Frequent RNF43 mutation contributes to moderate activation of Wnt signaling in colorectal signet-ring cell carcinoma

Yaqi Li ¹^,²
, Jian Li ³^,⁴
, Renjie Wang ¹^,²
, Long Zhang ¹^,²^,⁵
, Guoxiang Fu ⁶
, Xueying Wang ³^,⁴
, Yebin Wang ³^,⁴
, Chuantao Fang ³^,⁴
, Dandan Zhang ⁷
, Duo Du ⁷
, Xiaoji Ma ¹^,²
, Mengxue Pan ⁶
, Qiang Guo ⁶
, Xiaoya Xu ⁶
, Xiang Hu ¹^,²
, Yi Zhou ⁶
, Shaobo Mo ¹^,²
, Huijun Wang ³
, Jianjun Gao ⁶
, Shenglin Huang ⁸
, Yun Liu ⁷
, Sanjun Cai ¹^,²
, Guoqiang Hua ⁹^,^†
, Junjie Peng ¹^,²^,^†
, Fa-Xing Yu ³^,⁴^,^†

Author information +

¹. Department of Colorectal Surgery, Fudan University Shanghai Cancer Center, Shanghai 200032, China

². Department of Oncology, Shanghai Medical College, Fudan University, Shanghai 200032, China

³. Institute of Pediatrics, Children’s Hospital of Fudan University, Shanghai 200032, China

⁴. Key Laboratory of Medical Epigenetics and Metabolism, Institutes of Biomedical Sciences, Fudan University, Shanghai 200032, China

⁵. Cancer Institute, Fudan University Shanghai Cancer Center, Fudan University, Shanghai 200032, China

⁶. Institute of Radiation Medicine, Fudan University, Shanghai 200032, China

⁷. MOE Key Laboratory of Metabolism and Molecular Medicine, Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Fudan University, Shanghai 200032, China

⁸. Fudan University Shanghai Cancer Center and Institutes of Biomedical Sciences, Shanghai Medical College, Fudan University, Shanghai 200032, China

⁹. Institute of Radiation Medicine and Fudan University Shanghai Cancer Center, Shanghai Medical school, Fudan University, Shanghai 200032, China

Guoqiang Hua

Junjie Peng

Fa-Xing Yu

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Yaqi Li, Jian Li, Renjie Wang, Long Zhang, Guoxiang Fu, Xueying Wang, Yebin Wang, Chuantao Fang, Dandan Zhang, Duo Du, Xiaoji Ma, Mengxue Pan, Qiang Guo, Xiaoya Xu, Xiang Hu, Yi Zhou, Shaobo Mo, Huijun Wang, Jianjun Gao, Shenglin Huang, Yun Liu, Sanjun Cai, Guoqiang Hua, Junjie Peng, Fa-Xing Yu. Frequent RNF43 mutation contributes to moderate activation of Wnt signaling in colorectal signet-ring cell carcinoma. Protein Cell, 2020, 11(4): 292-298 DOI:10.1007/s13238-020-00691-0

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