Multiple sgRNAs facilitate base editingmediated i-stop to induce complete and precise gene disruption

Kun Jia; Zongyang Lu; Fei Zhou; Zhiqi Xiong; Rui Zhang; Zhiwei Liu; Yu’e Ma; Lei He; Cong Li; Zhen Zhu; Dejing Pan; Zhengxing Lian

doi:10.1007/s13238-019-0611-6

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Protein Cell ›› 2019, Vol. 10 ›› Issue (11) : 832-839. DOI: 10.1007/s13238-019-0611-6

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Multiple sgRNAs facilitate base editingmediated i-stop to induce complete and precise gene disruption

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Kun Jia, Zongyang Lu, Fei Zhou, Zhiqi Xiong, Rui Zhang, Zhiwei Liu, Yu’e Ma, Lei He, Cong Li, Zhen Zhu, Dejing Pan, Zhengxing Lian. Multiple sgRNAs facilitate base editingmediated i-stop to induce complete and precise gene disruption. Protein Cell, 2019, 10(11): 832‒839 https://doi.org/10.1007/s13238-019-0611-6

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