Hepatitis B virus is degraded by autophagosome-lysosome fusion mediated by Rab7 and related components

Yong Lin; Chunchen Wu; Xueyu Wang; Thekla Kemper; Anthony Squire; Matthias Gunzer; Jiming Zhang; Xinwen Chen; Mengji Lu

doi:10.1007/s13238-018-0555-2

PDF(3209 KB)

Protein Cell ›› 2019, Vol. 10 ›› Issue (1) : 60-66. DOI: 10.1007/s13238-018-0555-2

LETTER

Hepatitis B virus is degraded by autophagosome-lysosome fusion mediated by Rab7 and related components

Author information +

History +

Cite this article

EndNote

Ris (Procite)

Bibtex

Download citation ▾

Yong Lin, Chunchen Wu, Xueyu Wang, Thekla Kemper, Anthony Squire, Matthias Gunzer, Jiming Zhang, Xinwen Chen, Mengji Lu. Hepatitis B virus is degraded by autophagosome-lysosome fusion mediated by Rab7 and related components. Protein Cell, 2019, 10(1): 60‒66 https://doi.org/10.1007/s13238-018-0555-2

References

Publishing order | Descend order by publishing year | Descend order by cited within

[1]	Ding B, Zhang G, Yang X, Zhang S, Chen L, Yan Q, Xu M, Banerjee AK, Chen M (2014) Phosphoprotein of human parainfluenza virus type 3 blocks autophagosome-lysosome fusion to increase virus production . Cell Host Microbe 15:564–577 CrossRef Google scholar

[2]	Huovila AP, Eder AM, Fuller SD (1992) Hepatitis B surface antigen assembles in a post-ER, pre-Golgi compartment . J Cell Biol 118:1305–1320 CrossRef Google scholar

[3]	Inoue J, Krueger EW, Chen J, Cao H, Ninomiya M, McNiven MA (2015) HBV secretion is regulated through the activation of endocytic and autophagic compartments mediated by Rab7 stimulation . J Cell Sci 128:1696–1706 CrossRef Google scholar

[4]	Li J, Liu Y, Wang Z, Liu K, Wang Y, Liu J, Ding H, Yuan Z (2011) Subversion of cellular autophagy machinery by hepatitis B virus for viral envelopment . J Virol 85:6319–6333 CrossRef Google scholar

[5]	Lin Y, Deng W, Pang J, Kemper T, Hu J, Yin J, Zhang J, Lu M (2017) The microRNA-99 family modulates hepatitis B virus replication by promoting IGF-1R/PI3K/Akt/mTOR/ULK1 signaling-induced autophagy . Cell Microbiol 19:e12709 CrossRef Google scholar

[6]	Liu B, Fang M, Hu Y, Huang B, Li N, Chang C, Huang R, Xu X, Yang Z, Chen Z (2014) Hepatitis B virus X protein inhibits autophagic degradation by impairing lysosomal maturation . Autophagy 10:416–430 CrossRef Google scholar

[7]	McEwan DG, Popovic D, Gubas A, Terawaki S, Suzuki H, Stadel D, Coxon FP, Miranda de Stegmann D, Bhogaraju S, Maddi K (2015a) PLEKHM1 regulates autophagosome-lysosome fusion through HOPS complex and LC3/GABARAP proteins . Mol Cell 57:39–54 CrossRef Google scholar

[8]	McEwan DG, Richter B, Claudi B, Wigge C, Wild P, Farhan H, McGourty K, Coxon FP, Franz-Wachtel M, Perdu B (2015b) PLEKHM1 regulates Salmonella-containing vacuole biogenesis and infection . Cell Host Microbe 17:58–71 CrossRef Google scholar

[9]	Mizushima N, Komatsu M (2011) Autophagy: renovation of cells and tissues . Cell 147:728–741 CrossRef Google scholar

[10]	Patient R, Hourioux C, Roingeard P (2009) Morphogenesis of hepatitis B virus and its subviral envelope particles . Cell Microbiol 11:1561–1570 CrossRef Google scholar

[11]	Schweitzer A, Horn J, Mikolajczyk RT, Krause G, Ott JJ (2015) Estimations of worldwide prevalence of chronic hepatitis B virus infection: a systematic review of data published between 1965 and 2013 . Lancet 386:1546–1555 CrossRef Google scholar

[12]	Sir D, Tian YJ, Chen WL, Ann DK, Yen TSB, Ou JHJ (2010) The early autophagic pathway is activated by hepatitis B virus and required for viral DNA replication . Proc Natl Acad Sci USA 107:4383–4388 CrossRef Google scholar

[13]	Wang T, Ming Z, Xiaochun W, Hong W (2011) Rab7: role of its protein interaction cascades in endo-lysosomal traffic . Cell Signal 23:516–521 CrossRef Google scholar

[14]	Xie N, Yuan KF, Zhou L, Wang K, Chen HN, Lei YL, Lan J, Pu QQ, Gao W, Zhang L (2016) PRKAA/AMPK restricts HBV replication through promotion of autophagic degradation . Autophagy 12:1507–1520 CrossRef Google scholar