The structure differences of Japanese encephalitis virus SA14 and SA14-14-2 E proteins elucidate the virulence attenuation mechanism
Xinyu Liu, Xin Zhao, Rui Na, Lili Li, Eberhard Warkentin, Jennifer Witt, Xu Lu, Yongxin Yu, Yuquan Wei, Guohong Peng, Yuhua Li, Junzhi Wang
The structure differences of Japanese encephalitis virus SA14 and SA14-14-2 E proteins elucidate the virulence attenuation mechanism
[1] |
Aihara S, Rao CM, Yu YX, Lee T, Watanabe K, Komiya T, Sumiyoshi H, Hashimoto H, Nomoto A (1991) Identification of mutations that occurred on the genome of Japanese encephalitis virus during the attenuation process. Virus Genes 5(2):95–109
CrossRef
Google scholar
|
[2] |
Bressanelli S, Stiasny K, Allison SL, Stura EA, Duquerroy S, Lescar J, Heinz FX, Rey FA (2004) Structure of a flavivirus envelope glycoprotein in its low-pH-induced membrane fusion conformation. EMBO J 23(4):728–738
CrossRef
Google scholar
|
[3] |
Harrison SC (2015) Viral membrane fusion. Virology 479– 480:498–507
CrossRef
Google scholar
|
[4] |
Huang CY, Butrapet S, Moss KJ, Childers T, Erb SM, Calvert AE, Silengo SJ, Kinney RM, Blair CD, Roehrig JT (2010) The dengue virus type 2 envelope protein fusion peptide is essential for membrane fusion. Virology 396(2):305–315
CrossRef
Google scholar
|
[5] |
Luca VC, AbiMansour J, Nelson CA, Fremont DH (2012) Crystal structure of the Japanese encephalitis virus envelope protein. J Virol 86(4):2337–2346
CrossRef
Google scholar
|
[6] |
Modis Y, Ogata S, Clements D,Harrison SC (2003) A ligand-binding pocket in the dengue virus envelope glycoprotein. Proc Natl Acad Sci USA 100(12):6986–6991
CrossRef
Google scholar
|
[7] |
Modis Y, Ogata S, Clements D, Harrison SC (2004) Structure of the dengue virus envelope protein after membrane fusion. Nature 427(6972):313–319
CrossRef
Google scholar
|
[8] |
Mukhopadhyay S, Kuhn RJ, Rossmann MG (2005) A structural perspective of the flavivirus life cycle. Nat Rev Microbiol 3(1):13–22
CrossRef
Google scholar
|
[9] |
Wang X, Li SH, Zhu L, Nian QG, Yuan S, Gao Q, Hu Z, Ye Q, Li XF, Xie DY
CrossRef
Google scholar
|
[10] |
WHO: Japanese encephalitis. 2015, Fact sheet No 386
|
[11] |
Yang D, Li XF, Ye Q, Wang HJ, Deng YQ, Zhu SY, Zhang Y, Li SH, Qin CF (2014) Characterization of live-attenuated Japanese encephalitis vaccine virus SA14-14-2. Vaccine 32(23):2675–2681
CrossRef
Google scholar
|
[12] |
Yang J, Yang H, Li Z, Wang W, Lin H, Liu L, Ni Q, Liu X, Zeng X, Wu Y
CrossRef
Google scholar
|
[13] |
Yu Y (2010) Phenotypic and genotypic characteristics of Japanese encephalitis attenuated live vaccine virus SA14-14-2 and their stabilities. Vaccine 28(21):3635–3641
CrossRef
Google scholar
|
[14] |
Zhang Y, Zhang W, Ogata S, Clements D, Strauss JH, Baker TS, Kuhn RJ, Rossmann MG (2004) Conformational changes of the flavivirus E glycoprotein. Structure (London, England: 1993) 12 (9):1607–1618
CrossRef
Google scholar
|
[15] |
Zhang S, Li L, Woodson SE, Huang CY, Kinney RM, Barrett AD, Beasley DW (2006) A mutation in the envelope protein fusion loop attenuates mouse neuroinvasiveness of the NY99 strain of West Nile virus. Virology 353(1):35–40
CrossRef
Google scholar
|
/
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