UQCRFS1N assembles mitochondrial respiratory complex-III into an asymmetric 21-subunit dimer

Shuai Zong; Jinke Gu; Tianya Liu; Runyu Guo; Meng Wu; Maojun Yang

doi:10.1007/s13238-018-0515-x

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Protein Cell ›› 2018, Vol. 9 ›› Issue (6) : 586-591. DOI: 10.1007/s13238-018-0515-x

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UQCRFS1N assembles mitochondrial respiratory complex-III into an asymmetric 21-subunit dimer

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Shuai Zong, Jinke Gu, Tianya Liu, Runyu Guo, Meng Wu, Maojun Yang. UQCRFS1N assembles mitochondrial respiratory complex-III into an asymmetric 21-subunit dimer. Protein Cell, 2018, 9(6): 586‒591 https://doi.org/10.1007/s13238-018-0515-x

References

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[1]	Baradaran R, Berrisford JM, Minhas GS, Sazanov LA (2013) Crystal structure of the entire respiratory complex I. Nature 494:443–448 CrossRef Google scholar

[2]	Bottani E, Cerutti R, Harbour ME, Ravaglia S, Dogan SA, Giordano C, Fearnley IM, D’Amati G, Viscomi C, Fernandez-Vizarra E (2017) TTC19 plays a husbandry role on UQCRFS1 turnover in the biogenesis of mitochondrial respiratory complex III. Mol Cell 67(96–105):e104 CrossRef Google scholar

[3]	Deng K, Shenoy SK, Tso SC, Yu L, Yu CA (2001) Reconstitution of mitochondrial processing peptidase from the core proteins (subunits I and II) of bovine heart mitochondrial cytochrome bc (1) complex. J Biol Chem 276:6499–6505 CrossRef Google scholar

[4]	Fernandez-Vizarra E, Zeviani M (2015) Nuclear gene mutations as the cause of mitochondrial complex III deficiency. Front Genet 6:134 CrossRef Google scholar

[5]	Fernandez-Vizarra E, Zeviani M (2017) Mitochondrial complex III Rieske Fe-S protein processing and assembly. Cell Cycle1–25.

[6]	Gu J, Wu M, Guo R, Yan K, Lei J, Gao N, Yang M (2016) The architecture of the mammalian respirasome. Nature 537:639–643 CrossRef Google scholar

[7]	Guo R, Gu J, Wu M, Yang M (2016) Amazing structure of respirasome: unveiling the secrets of cell respiration. Protein Cell 7:854–865 CrossRef Google scholar

[8]	Guo R, Zong S, Wu M, Gu J, Yang M (2017) Architecture of human mitochondrial respiratory megacomplex I2III2IV2. Cell 170(1247–1257):e1212

[9]	Hao GF, Wang F, Li H, Zhu XL, Yang WC, Huang LS, Wu JW, Berry EA, Yang GF (2012) Computational discovery of picomolar Q (o) site inhibitors of cytochrome bc1 complex. J Am Chem Soc 134:11168–11176 CrossRef Google scholar

[10]	Huang LS, Cobessi D, Tung EY, Berry EA (2005) Binding of the respiratory chain inhibitor antimycin to the mitochondrial bc1 complex: a new crystal structure reveals an altered intramolecular hydrogen-bonding pattern. J Mol Biol 351:573–597 CrossRef Google scholar

[11]	Schagger H, Pfeiffer K (2000) Supercomplexes in the respiratory chains of yeast and mammalian mitochondria. EMBO J 19:1777–1783 CrossRef Google scholar

[12]	Vinothkumar KR, Zhu J, Hirst J (2014) Architecture of mammalian respiratory complex I. Nature 515:80–84 CrossRef Google scholar

[13]	Wai T, Saita S, Nolte H, Muller S, Konig T, Richter-Dennerlein R, Sprenger HG, Madrenas J, Muhlmeister M, Brandt U (2016) The membrane scaffold SLP2 anchors a proteolytic hub in mitochondria containing PARL and the i-AAA protease YME1L. EMBO Rep 17:1844–1856 CrossRef Google scholar

[14]	Wu M, Gu J, Guo R, Huang Y, Yang M (2016) Structure of mammalian respiratory supercomplex I1III2IV1. Cell 167(1598–1609):e1510

[15]	Xia D, Yu CA, Kim H, Xia JZ, Kachurin AM, Zhang L, Yu L, Deisenhofer J (1997) Crystal structure of the cytochrome bc1 complex from bovine heart mitochondria. Science 277:60–66 CrossRef Google scholar