MD simulation of high-resolution X-ray structures reveals post-translational modification dependent conformational changes in HSF-DNA interaction
Han Feng, Sheng Wang, Ling Guo, Avinash S. Punekar, Rudolf Ladenstein, Da-Cheng Wang, Wei Liu
MD simulation of high-resolution X-ray structures reveals post-translational modification dependent conformational changes in HSF-DNA interaction
[1] |
Akerfelt M, Morimoto RI, Sistonen L (2010) Heat shock factors: integrators of cell stress, development and lifespan. Nat Rev Mol Cell Biol 11(8):545–555
CrossRef
Google scholar
|
[2] |
Anckar J, Hietakangas V, Denessiouk K, Thiele DJ, Johnson MS, Sistonen L (2006) Inhibition of DNA binding by differential sumoylation of heat shock factors. Mol Cell Biol 26(3):955–964
CrossRef
Google scholar
|
[3] |
Bjork JK, Sistonen L (2010) Regulation of the members of the mammalian heat shock factor family. FEBS J 277(20):4126–4139
CrossRef
Google scholar
|
[4] |
Dai C, Whitesell L, Rogers AB, Lindquist S (2007) Heat shock factor 1 is a powerful multifaceted modifier of carcinogenesis. Cell 130 (6):1005–1018
CrossRef
Google scholar
|
[5] |
Feng H, Liu W, Wang DC (2016) Purification, crystallization and X-ray diffraction analysis of the DNA-binding domain of human heat-shock factor 2. Acta Crystallogr F Struct Biol Commun 72(Pt 4):294–299
CrossRef
Google scholar
|
[6] |
Jaeger AM, Pemble CW, Sistonen L, Thiele DJ (2016) Structures of HSF2 reveal mechanisms for differential regulation of human heat-shock factors. Nat Struct Mol Biol 23(2):147–154
CrossRef
Google scholar
|
[7] |
Littlefield O, Nelson HC (1999) A new use for the ‘wing’ of the ‘winged’ helix-turn-helix motif in the HSF-DNA cocrystal. Nat Struct Biol 6(5):464–470
CrossRef
Google scholar
|
[8] |
Neef DW, Jaeger AM, Thiele DJ (2011) Heat shock transcription factor 1 as a therapeutic target in neurodegenerative diseases. Nat Rev Drug Discov 10(12):930–944
CrossRef
Google scholar
|
[9] |
Neudegger T, Verghese J, Hayer-Hartl M, Hartl FU, Bracher A (2016) Structure of human heat-shock transcription factor 1 in complex with DNA. Nat Struct Mol Biol 23(2):140–146
CrossRef
Google scholar
|
[10] |
Rohs R, West SM, Sosinsky A, Liu P, Mann RS, Honig B (2009) The role of DNA shape in protein-DNA recognition. Nature 461 (7268):1248–1253
CrossRef
Google scholar
|
[11] |
Scherz-Shouval R, Santagata S, Mendillo ML, Sholl LM, Ben-Aharon I, Beck AH, Dias-Santagata D, Koeva M, Stemmer SM, Whitesell L, Lindquist S (2014) The reprogramming of tumor stroma by HSF1 is a potent enabler of malignancy. Cell 158 (3):564–578
CrossRef
Google scholar
|
[12] |
Tateishi Y, Ariyoshi M, Igarashi R, Hara H, Mizuguchi K, Seto A, Nakai A, Kokubo T, Tochio H, Shirakawa M (2009) Molecular basis for SUMOylation-dependent regulation of DNA binding activity of heat shock factor 2. J Biol Chem 284(4):2435–2447
CrossRef
Google scholar
|
[13] |
Westerheide SD, Anckar J, Stevens SM Jr, Sistonen L, Morimoto RI (2009) Stress-inducible regulation of heat shock factor 1 by the deacetylase SIRT1. Science 323(5917):1063–1066
CrossRef
Google scholar
|
[14] |
Westerheide SD, Raynes R, Powell C, Xue B, Uversky VN (2012) HSF transcription factor family, heat shock response, and protein intrinsic disorder. Curr Protein Pept Sci 13(1):86–103
CrossRef
Google scholar
|
[15] |
Xing H, Wilkerson DC, Mayhew CN, Lubert EJ, Skaggs HS, Goodson ML, Hong Y, Park-Sarge OK, Sarge KD (2005) Mechanism of hsp70i gene bookmarking. Science 307 (5708):421–423
CrossRef
Google scholar
|
/
〈 | 〉 |