The role of endosomal cholesterol trafficking protein, StAR-related lipid transfer domain 3 (StarD3/MLN64), in BRIN-BD11 insulinoma cells
Joana Borges Pinto, Annette Graham
The role of endosomal cholesterol trafficking protein, StAR-related lipid transfer domain 3 (StarD3/MLN64), in BRIN-BD11 insulinoma cells
[1] |
Alpy F, Rousseau A, Schwab Y, Legueux F, Stoll I, Wendling C, Spiegelhalter C, Kessler P, Mathelin C, Rio MC, Levine TP, Tomasetto C (2013) STARD3 or STARD3NL and VAP form a novel molecular tether between late endosomes and the ER. J Cell Sci 126:5500–5512
CrossRef
Google scholar
|
[2] |
Borthwick F, Taylor JM, Bartholomew C, Graham A (2009) Differential regulation of the STARD1 subfamily of START lipid trafficking proteins in human (THP-1) macrophages. FEBS Lett 583:1147–1153
CrossRef
Google scholar
|
[3] |
Borthwick F, Allen AM, Taylor JM, Graham A (2010) Over-expression of STARD3 in human monocyte-macrophages induces an antiatherogenic lipid phenotype. Clin Sci (Lond) 119:265–272
CrossRef
Google scholar
|
[4] |
Charman M, Kennedy BE, Osborne N, Karten B (2010) MLN64 mediates egress of cholesterol from endosomes to mitochondria in the absence of functional Niemann-Pick Type C1 protein. J Lipid Res 51:1023–1034
CrossRef
Google scholar
|
[5] |
Holtta-Vuori M, Alpy F, Tanhaunapaa K, Jokitalo E, Mutka AL, Ikonen E (2005) MLN64 is involved in actin-mediated dynamics of late endocytic organelles. Mol Biol Cell 16:3873–3886
CrossRef
Google scholar
|
[6] |
Kijlstra A, Tian Y, Kelly ER, Berendschot TT (2012) Lutein: more than just a filter for blue light. Prog Retin Eye Res 31:303–315
CrossRef
Google scholar
|
[7] |
Kishida T, Kostetskii I, Zhang Z, Martinez F, Liu P, Walkley SU, Dwyer NK, Blanchette-Mackie EJ, Radice GL, Strauss JF 3rd (2004) Targeted mutation of the MLN64 START domain causes only modest alterations in cellular sterol metabolism. J Biol Chem 279:19276–19285
CrossRef
Google scholar
|
[8] |
Kruit JK, Wijesekara N, Westwell-Roper C, Vanmierlo T, de Haan W, Bhattacharjee A, Tang R, Welling CL, LutJohann D, Johnson KD, Brunham LR, Verchere CB, Hayden MR (2012) Loss of both ABCA1 and ABCG1 results in increased disturbances in islet sterol homeostasis, inflammation and impaired β-cell function. Diabetes 61:659–664
CrossRef
Google scholar
|
[9] |
Li B, Vachali P, Frederick JM, Bernstein PS (2011) Identification of StARD3 as a lutein-binding protein in the macula of the primate retina. Biochemistry 50:2541–2549
CrossRef
Google scholar
|
[10] |
Rutti S, Ehses JA, Sibler RA, Prazak R, Rohrer L, Georgopoulos S, Meier DT, Niclauss N, Berney T, Donath MY, von Eckardstein A (2009) Low- and high-density lipoproteins modulate function, apoptosis and proliferation of primary human and murine pancreatic beta-cells. Endocrinology 150:4521–4530
CrossRef
Google scholar
|
[11] |
Soffientini U, Caridis A-M, Dolan S, Graham A (2014) Intracellular cholesterol transporters and modulation of hepatic lipid metabolism: implications for diabetic dyslipidaemia and steatosis. Biochim Biophys Acta 1841:1372–1382
CrossRef
Google scholar
|
[12] |
Souza JC, Vanzela EC, Ribeiro RA, Rezende LF, de Oliveira CA, Carneiro EM, Oliveira HC, Boschero AC (2013) Cholesterol reduction ameliorates glucose-induced calcium handling and insulin secretion in islets from low-density lipoprotein receptor knockout mice. Biochim Biophys Acta 1831:769–775
CrossRef
Google scholar
|
[13] |
Tsuchiya M, Hosaka M, Moriguchi T, Zhang S, Suda M, Yokota-Hashimoto H, Shinozuka K, Takeuchi T (2010) Cholesterol biosynthesis pathway intermediates and inhibitors regulate glucose-stimulated insulin secretion and secretory granule formation in pancreatic beta cells. Endocrinology 151:4705–4716
CrossRef
Google scholar
|
[14] |
van der Kant R, Zondervan I, Jansse L, Neefjes J (2013) Cholesterol-binding molecules MLN64 and ORP1L mark distinct late endosomes with transporters ABCA3 and NPC1. J Lipid Res 54:2153–2165
CrossRef
Google scholar
|
[15] |
Zuniga-Hertz JP, Rebelato E, Kassan A, Khalifa AM, Ali SS, Patel HH, Abdulkader F (2015) Distinct pathways of cholesterol biosynthesis impact on insulin secretion. J Endocrinol 224: 75–84
CrossRef
Google scholar
|
/
〈 | 〉 |