The crystal structure of Zika virus helicase: basis for antiviral drug design

Hongliang Tian, Xiaoyun Ji, Xiaoyun Yang, Wei Xie, Kailin Yang, Cheng Chen, Chen Wu, Heng Chi, Zhongyu Mu, Zefang Wang, Haitao Yang

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Protein Cell ›› 2016, Vol. 7 ›› Issue (6) : 450-454. DOI: 10.1007/s13238-016-0275-4
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The crystal structure of Zika virus helicase: basis for antiviral drug design

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Hongliang Tian, Xiaoyun Ji, Xiaoyun Yang, Wei Xie, Kailin Yang, Cheng Chen, Chen Wu, Heng Chi, Zhongyu Mu, Zefang Wang, Haitao Yang. The crystal structure of Zika virus helicase: basis for antiviral drug design. Protein Cell, 2016, 7(6): 450‒454 https://doi.org/10.1007/s13238-016-0275-4

References

[1]
Brasil P, Pereira JP Jr, Raja Gabaglia C, Damasceno L, Wakimoto M, Ribeiro Nogueira RM, Carvalho de Sequeira P, Machado Siqueira A, Abreu de Carvalho LM, Cotrim da Cunha D (2016) Zika virus infection in pregnant women in Rio de Janeiro—preliminary report . N Engl J Med.
CrossRef Google scholar
[2]
Caruthers JM, McKay DB (2002) Helicase structure and mechanism . Curr Opin Struct Biol 12:123–133
CrossRef Google scholar
[3]
Felsenstein J (1997) An alternating least squares approach to inferring phylogenies from pairwise distances . Syst Biol 46: 101–111
CrossRef Google scholar
[4]
Hennessey M, Fischer M, Staples JE (2016) Zika virus spreads to new areas—region of the Americas, May 2015-January 2016 . Morb Mortal Wkly Rep 65:55–58
CrossRef Google scholar
[5]
Ioos S, Mallet HP, Leparc Goffart I, Gauthier V, Cardoso T, Herida M (2014) Current Zika virus epidemiology and recent epidemics . Med Mal Infect 44:302–307
CrossRef Google scholar
[6]
Lazear HM, Diamond MS (2016) Zika virus: new clinical syndromes and its emergence in the Western Hemisphere . J Virol.
CrossRef Google scholar
[7]
Lindenbach BD, Rice CM (2001) Fundamental virology . Lippincott-Raven, Philadelphia
[8]
Luo D, Xu T, Watson RP, Scherer-Becker D, Sampath A, Jahnke W, Yeong SS, Wang CH, Lim SP, Strongin A (2008) Insights into RNA unwinding and ATP hydrolysis by the flavivirus NS3 protein . EMBO J 27:3209–3219
CrossRef Google scholar
[9]
Mlakar J, Korva M, Tul N, Popovic M, Poljsak-Prijatelj M, Mraz J, Kolenc M, Resman Rus K, Vesnaver Vipotnik T, Fabjan Vodusek V (2016) Zika virus associated with microcephaly . N Engl J Med 374:951–958
CrossRef Google scholar
[10]
Pierson TC, Diamond (2013) Flaviviruses, vol 2, 6th edn. Wolter Kluwer, Philadelphia Rodrigues LC (2016) Microcephaly and Zika virus infection . Lancet.
CrossRef Google scholar
[11]
Stuart DI, Levine M, Muirhead H, Stammers DK (1979) Crystal structure of cat muscle pyruvate kinase at a resolution of 2.6 Å . J Mol Biol 134:109–142
CrossRef Google scholar
[12]
Tang H, Hammack C, Ogden SC, Wen Z, Qian X, Li Y, Yao B, Shin J, Zhang F, Lee EM (2016) Zika virus infects human cortical neural progenitors and attenuates their growth . Cell Stem Cell.
CrossRef Google scholar
[13]
Xu T, Sampath A, Chao A, Wen D, Nanao M, Chene P, Vasudevan SG, Lescar J (2005) Structure of the Dengue virus helicase/nucleoside triphosphatase catalytic domain at a resolution of 2.4 Å . J Virol 79:10278–10288
CrossRef Google scholar

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2016 The Author(s) 2016. This article is published with open access at Springerlink.com and journal.hep.com.cn
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