FMRP: a new chapter with chromatin

Qingzhong He, Wei Ge

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PDF(154 KB)
Protein Cell ›› 2014, Vol. 5 ›› Issue (12) : 885-888. DOI: 10.1007/s13238-014-0105-5
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FMRP: a new chapter with chromatin

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Qingzhong He, Wei Ge. FMRP: a new chapter with chromatin. Protein Cell, 2014, 5(12): 885‒888 https://doi.org/10.1007/s13238-014-0105-5

References

[1]
Alpatov R, Lesch BJ, Nakamoto-Kinoshita M, Blanco A, Chen S, Stutzer A, Armache KJ, Simon MD, Xu C, Ali M (2014) A Chromatin-dependent role of the fragile X mental retardation protein FMRP in the DNA damage response. Cell157: 869-881
CrossRef Google scholar
[2]
Blonden L, van ‘t Padje S, Severijnen LA, Destree O, Oostra BA, Willemsen R (2005) Two members of the Fxr gene family, Fmr1 and Fxr1, are differentially expressed in Xenopus tropicalis. Int J Dev Biol49: 437-441
CrossRef Google scholar
[3]
Corbin F, Bouillon M, Fortin A, Morin S, Rousseau F, Khandjian EW (1997) The fragile X mental retardation protein is associated with poly(A)(+) mRNA in actively translating polyribosomes. Hum Mol Genet6: 1465-1472
CrossRef Google scholar
[4]
Feng Y, Gutekunst CA, Eberhart DE, Yi H, Warren ST, Hersch SM (1997) Fragile X mental retardation protein: nucleocytoplasmic shuttling and association with somatodendritic ribosomes. J Neurosci: Off J Soc Neurosci17: 1539-1547
[5]
Isabelle M, Moreel X, Gagne JP, Rouleau M, Ethier C, Gagne P, Hendzel MJ, Poirier GG (2010) Investigation of PARP-1, PARP-2, and PARG interactomes by affinity-purification mass spectrometry. Proteome Sci8: 22
CrossRef Google scholar
[6]
Khandjian EW, Corbin F, Woerly S, Rousseau F (1996) The fragile X mental retardation protein is associated with ribosomes. Nature Genet12: 91-93
CrossRef Google scholar
[7]
Kim M, Bellini M, Ceman S (2009) Fragile X mental retardation protein FMRP binds mRNAs in the nucleus. Mol Cell Biol29: 214-228
CrossRef Google scholar
[8]
Kobayashi J, Fujimoto H, Sato J, Hayashi I, Burma S, Matsuura S, Chen DJ, Komatsu K (2012) Nucleolin participates in DNA double-strand break-induced damage response through MDC1-dependent pathway. PloS one7: e49245
CrossRef Google scholar
[9]
Maurer-Stroh S, Dickens NJ, Hughes-Davies L, Kouzarides T, Eisenhaber F, Ponting CP (2003) The tudor domain ‘Royal Family’: tudor, plant agenet, chromo, PWWP and MBT domains. Trends Biochem Sci28: 69-74
CrossRef Google scholar
[10]
Ramos A, Hollingworth D, Adinolfi S, Castets M, Kelly G, Frenkiel TA, Bardoni B, Pastore A(2006) The structure of the N-terminal domain of the fragile X mental retardation protein: a platform for proteinprotein interaction. Structure (London, England : 1993)14: 21-31
CrossRef Google scholar
[11]
Reeve SP, Lin X, Sahin BH, Jiang F, Yao A, Liu Z, Zhi H, Broadie K, Li W, Giangrande A (2008) Mutational analysis establishes a critical role for the N terminus of fragile X mental retardation protein FMRP. J Neurosci: Off J Soc Neurosci28: 3221-3226
CrossRef Google scholar
[12]
Slegtenhorst-Eegdeman KE, de Rooij DG, Verhoef-Post M, van de Kant HJ, Bakker CE, Oostra BA, Grootegoed JA, Themmen AP (1998) Macroorchidism in FMR1 knockout mice is caused by increased Sertoli cell proliferation during testicular development. Endocrinology139: 156-162
[13]
Taha MS, Nouri K, Milroy LG, Moll JM, Herrmann C, Brunsveld L, Piekorz RP, Ahmadian MR (2014) Subcellular fractionation and localization studies reveal a direct interaction of the fragile X mental retardation protein (FMRP) with nucleolin. PloS one9: e91465
CrossRef Google scholar
[14]
Van ‘t Padje S, Engels B, Blonden L, Severijnen LA, Verheijen F, Oostra BA, Willemsen R(2005) Characterisation of Fmrp in zebrafish: evolutionary dynamics of the fmr1 gene. Dev Genes Evol215: 198-206
CrossRef Google scholar
[15]
Zhang W, Cheng Y, Li Y, Chen Z, Jin P, and Chen D (2014). A feedforward mechanism involving Drosophila fragile X mental retardation protein triggers a replication stress-induced DNA damage response. Hum Mol Genet
CrossRef Google scholar

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2014 This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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