[1] Bruns, A., Bl?ss, S., Hausdorf, G., Burmester, G.R., and Hiepe, F. (2000). Nucleosomes are major T and B cell autoantigens in systemic lupus erythematosus.
Arthritis Rheum 43, 2307-2315 11037891
[2] Bürglin, T.R. (1997). Analysis of TALE superclass homeobox genes (MEIS, PBC, KNOX, Iroquois, TGIF) reveals a novel domain conserved between plants and animals.
Nucleic Acids Res 25, 4173-4180 9336443
[3] Chen, Y., Cuda, C.M., and Morel, L. (2005). Genetic determination of T cell help in loss of tolerance to nuclear antigens.
J Immunol 174, 7692-7702 15944270
[4] Cuda, C.M., Li, S., Liang, S., Yin, Y., Potula, H.H., Xu, Z., Sengupta, M., Chen, Y., Butfiloski, E., Barker, H., Chang, L., Dozmorov, I., Sobel, E.S. and Morel, L. Pre-B cell leukemia homeobox 1 is associated with lupus susceptibility in mice and humans.
J Immunol. (In press)
[5] Cuda, C.M., Wan, S., Sobel, E.S., Croker, B.P., and Morel, L. (2007). Murine lupus susceptibility locus Sle1a controls regulatory T cell number and function through multiple mechanisms.
J Immunol 179, 7439-7447 18025188
[6] Gordon, J.A.R., Hassan, M.Q., Saini, S., Montecino, M., van Wijnen, A.J., Stein, G.S., Stein, J.L., and Lian, J.B. (2010). Pbx1 represses osteoblastogenesis by blocking Hoxa10-mediated recruitment of chromatin remodeling factors.
Mol Cell Biol 30, 3531-3541 20439491
[7] Humrich, J.Y., Morbach, H., Undeutsch, R., Enghard, P., Rosenberger, S., Weigert, O., Kloke, L., Heimann, J., Gaber, T., Brandenburg, S.,
(2010). Homeostatic imbalance of regulatory and effector T cells due to IL-2 deprivation amplifies murine lupus.
Proc Natl Acad Sci U S A 107, 204-209 20018660
[8] La Cava, A. (2009). Lupus and T cells.
Lupus 18, 196-201 19213856
[9] Langer, S., Langnickel, D., Enghard, P., Undeutsch, R., Burmester, G.R., Hiepe, F., Radbruch, A., and Riemekasten, G. (2007). The systemic and SmD183-119-autoantigenspecific cytokine memory of Th cells in SLE patients.
Rheumatol 46, 238-245 .
[10] Morel, L. (2010) Genetics of SLE: Evidence from mouse models
. Nat Rev Rheumatol .
10.1038/nrrheum.2010.63[11] Morel, L., Croker, B.P., Blenman, K.R., Mohan, C., Huang, G., Gilkeson, G., and Wakeland, E.K. (2000). Genetic reconstitution of systemic lupus erythematosus immunopathology with polycongenic murine strains.
Proc Natl Acad Sci U S A 97, 6670-6675 10841565
[12] Morel, L., Mohan, C., Yu, Y., Croker, B.P., Tian, N., Deng, A., and Wakeland, E.K. (1997). Functional dissection of systemic lupus erythematosus using congenic mouse strains.
J Immunol 158, 6019-6028 9190957
[13] Morel, L., Rudofsky, U.H., Longmate, J.A., Schiffenbauer, J., and Wakeland, E.K. (1994). Polygenic control of susceptibility to murine systemic lupus erythematosus.
Immunity 1, 219-229 7889410
[14] Morel, L., and Wakeland, E.K. (1998). Susceptibility to lupus nephritis in the NZB/W model system.
Curr Opin Immunol 10, 718-725 9914223
[15] Perry, D., Sang, A., Yin, Y., Zheng, Y.Y., and Morel, L. (2011). Murine models of systemic lupus erythematosus.
J Biomed Biotechnol 2011, 27169421403825
[16] Qin, P., Haberbusch, J.M., Zhang, Z., Soprano, K.J., and Soprano, D.R. (2004). Pre-B cell leukemia transcription factor (PBX) proteins are important mediators for retinoic acid-dependent endodermal and neuronal differentiation of mouse embryonal carcinoma P19 cells.
J Biol Chem 279, 16263-16271 14742427
[17] Rhee, J.W., Arata, A., Selleri, L., Jacobs, Y., Arata, S., Onimaru, H., and Cleary, M.L. (2004). Pbx3 deficiency results in central hypoventilation.
Am J Pathol 165, 1343-1350 15466398
[18] Sakaguchi, S., Setoguchi, R., Yagi, H., and Nomura, T. (2006). Naturally arising Foxp3-expressing CD25+CD4+ regulatory T cells in self-tolerance and autoimmune disease.
Curr Top Microbiol Immunol 305, 51-66 16724800
[19] Selleri, L., DiMartino, J., van Deursen, J., Brendolan, A., Sanyal, M., Boon, E., Capellini, T., Smith, K.S., Rhee, J., P?pperl, H.,
(2004). The TALE homeodomain protein Pbx2 is not essential for development and long-term survival.
Mol Cell Biol 24, 5324-5331 15169896
[20] Shah, D., Aggarwal, A., Bhatnagar, A., Kiran, R., and Wanchu, A. (2011). Association between T lymphocyte sub-sets apoptosis and peripheral blood mononuclear cells oxidative stress in systemic lupus erythematosus.
Free Radic Res 45, 559-567 21284579
[21] Shlomchik, M.J., Craft, J.E., and Mamula, M.J. (2001). From T to B and back again: positive feedback in systemic autoimmune disease.
Nat Rev Immunol 1, 147-153 11905822
[22] Sobel, E.S., Brusko, T.M., Butfiloski, E.J., Hou, W., Li, S., Cuda, C.M., Abid, A.N., Reeves, W.H. and Morel, L. (2011) Defective response of CD4+ T cells to retinoic acid and TGFβ in systemic lupus erythematosus
. Arthritis Res Ther 27 , 13, R106.
[23] Theofilopoulos, A.N. (1993). In: Systemic Lupus Erythematosus. Lahita, R. G. ed.
New York:
Churchill Livingstone. 121-194 .
[24] Tsao, B.P., and Grossman, J.M. (2001). Genetics and systemic lupus erythematosus.
Curr Rheumatol Rep 3, 183-190 11352786.
[25] Vyse, T.J., and Kotzin, B.L. (1998). Genetic susceptibility to systemic lupus erythematosus.
Annu Rev Immunol 16, 261-292 9597131
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