Tumor-Derived Autophagosomes Coated With Nanodots as Future Personalized Cancer Vaccines

Lantian Lu; Mariusz Skwarczynski

doi:10.1002/mef2.70015

MEDCOMM - Future Medicine ›› 2025, Vol. 4 ›› Issue (1) : e70015 DOI: 10.1002/mef2.70015

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Tumor-Derived Autophagosomes Coated With Nanodots as Future Personalized Cancer Vaccines

Lantian Lu ¹^,²
, Mariusz Skwarczynski ¹^,^†

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Lantian Lu, Mariusz Skwarczynski. Tumor-Derived Autophagosomes Coated With Nanodots as Future Personalized Cancer Vaccines. MEDCOMM - Future Medicine, 2025, 4(1): e70015 DOI:10.1002/mef2.70015

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References

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[1]	W.-Q.Huang, W.You, and Y.-Q.Zhu, et al. “Autophagosomes Coated In Situ With Nanodots Act as Personalized Cancer Vaccines,” Nature Nanotechnology 2025, ahead of print.

[2]	L.Galluzzi, J. M.Bravo-San Pedro, B.Levine, D. R.Green, and G.Kroemer, “Pharmacological Modulation of Autophagy: Therapeutic Potential and Persisting Obstacles,” Nature Reviews Drug Discovery 16, no. 7 (2017):487–511.

[3]	M.Skwarczynski, G.Zhao, J. C.Boer, et al., “Poly(Amino Acids) as a Potent Self-Adjuvanting Delivery System for Peptide-Based Nanovaccines,” Science Advances 6, no. 5 (2020): eaax2285.

[4]	G.Zhao, H. D.Sathkumara, S.Miranda-Hernandez, et al., “A Modular Self-Assembling and Self-Adjuvanting Multiepitope Peptide Nanoparticle Vaccine Platform to Improve the Efficacy and Immunogenicity of BCG,” Small 21 (2025): e2406874

[5]	K.-IHanada, C.Zhao, R.Gil-Hoyos, et al., “A Phenotypic Signature That Identifies Neoantigen-Reactive T Cells in Fresh Human Lung Cancers,” Cancer Cell 40, no. 5 (2022):479–493.e6.

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