Unlocking longevity: How blocking IL-11 signaling could extend healthspan and lifespan

L. S. C. Lok; O. Monteiro; D. T. Baptista-Hon

doi:10.1002/mef2.101

MEDCOMM - Future Medicine ›› 2024, Vol. 3 ›› Issue (4) : e101 DOI: 10.1002/mef2.101

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Unlocking longevity: How blocking IL-11 signaling could extend healthspan and lifespan

L. S. C. Lok ¹
, O. Monteiro ¹^,²^,³
, D. T. Baptista-Hon ¹^,²^,³^,^†

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L. S. C. Lok, O. Monteiro, D. T. Baptista-Hon. Unlocking longevity: How blocking IL-11 signaling could extend healthspan and lifespan. MEDCOMM - Future Medicine, 2024, 3(4): e101 DOI:10.1002/mef2.101

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References

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[1]	WidjajaAA, LimWW, ViswanathanS, et al. Inhibition of IL-11 signalling extends mammalian healthspan and lifespan. Nature. 2024;632:157-165.

[2]	CookSA, Schafer S. Hiding in plain sight: interleukin-11 emerges as a master regulator of fibrosis, tissue integrity, and stromal inflammation. Annu Rev Med. 2020;71:263-276.

[3]	AlderJK, Armanios M. Telomere-mediated lung disease. Physiol Rev. 2022;102(4):1703-1720.

[4]	WangJ, GaoY, WangF, et al. Accurate estimation of biological age and its application in disease prediction using a multimodal image Transformer system. Proc Nat Acad Sci. 2024;121(3):e2308812120.

[5]	LiZ, ZhangW, DuanY, et al. Progress in biological age research. Front Public Health. 2023;11:1074274.

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2024 The Author(s). MedComm - Future Medicine published by John Wiley & Sons Australia, Ltd on behalf of Sichuan International Medical Exchange & Promotion Association (SCIMEA).