Hyperglycemia induced by clozapine and its alternative therapy: a case report

Abstract

Clozapine has been recognized as the best drug for the treatment of refractory schizophrenia, but its clinical use is very cautious. Clozapine has many side effects, among which agranulocytosis is fatal. And it often causes glucose intolerance, leading to type 2 diabetes. The treatment plan for elevated blood glucose in clozapine patients is still unclear. This paper will report one case of glucose intolerance caused by clozapine and its alternative treatment, and discuss the treatment plan.

Keywords

schizophrenia / clozapine / glucose intolerance / alternative therapy