Simultaneous spectrophotometric determination of three components including deoxyschizandrin by partial least squares regression

Abstract

The computer auxiliary partial least squares is introduced to simultaneously determine the contents of Deoxyschizandin, Schisandrin, γ-Schisandrin in the extracted solution of wuweizi. Regression analysis of the experimental results shows that the average recovery of each component is all in the range from 98.9% to 110.3%, which means the partial least squares regression spectrophotometry can circumvent the overlapping of absorption spectrums of multi-components, so that satisfactory results can be obtained without any sample pre-separation.

Keywords

Deoxyschizandrin / partial least squares regression spectrophotometry / simultaneous determination

References

[1] Hewala Ismail I. High-Performance Liquid Chromatographic and Derivative Difference Speetrophotometric Methods for the Determination of Acetaminophen and Its Degradation Product in Aged Pharmaceutical Formulations. Anal. Lett., 1994, 27(3): 561-564.

[2] Liqing Zhang, Xi Tang, Xianliang Zhu. The Simultaneous Determination of Five Components Including Acetaminophen by Ridge Regression Spectrophotometry. Journal of Wuhan University of Technology-Materials Science Edition, 2001, 16(2): 79-82.

[3] Li-qing Zhang, Xiao-hua Wu, Xi Tang, Xian-liang Zhu, Wen-ting Su. Simultaneous Spectrophotometric Determination of Five-Components in Cough Syrup by Partial Least Squares. Journal of Analytical Science, 2002, 18(4): 318-320.

[4] Peiceng Gong, Weimin Lu, Zhiqiang Yang. Visual Basic Programming, 1998 Perking: Higher Education Press. 58-58.

[5] Guozhen Chen, Xianzhi Huang, Wenyuan Liu, . UV-VIS Spectrophotometry, 1983 Beijing: Atomic Energy Press. 167-174.

[6] Jixiang Zhou. Practical Regression Analytical Method, 1990 Shanghai: Shanghai Scientific and Technical Publishers. 122-122.

[7] Dezhao Chen. Multivariate Processing, 1998 Beijing: Chemical Industry Press.

[8] Kaitai Fang, Changxing Ma. Orthogonal and Uniform Experiment Design, 2001 Beijing: Science Press. 152-178.