Efficacy and Safety of Xiaoer Chiqiao Qingre Syrup in the Treatment of Pedo-Anemopyretic Cold With Stagnant Syndrome in Children: A Multicenter, Randomized, Double-Blind, Double-Dummy, Parallel, Positive-Controlled, Noninferiority Trial

Chengliang Zhong; Shengxuan Guo; Yimin Yang; Aizhen Wang; Zheng Xue; Mengqing Wang; Guihua Song; Kun Yang; Hai Wang; Wei Zhong; Ya Gao; Zhigang Liu; Minghui Wang; Yuyan Chen; Xinmin Li; Siyuan Hu

doi:10.1111/jebm.70077

Journal of Evidence-Based Medicine ›› 2025, Vol. 18 ›› Issue (3) : e70077 DOI: 10.1111/jebm.70077

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Efficacy and Safety of Xiaoer Chiqiao Qingre Syrup in the Treatment of Pedo-Anemopyretic Cold With Stagnant Syndrome in Children: A Multicenter, Randomized, Double-Blind, Double-Dummy, Parallel, Positive-Controlled, Noninferiority Trial

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¹. Department of Pediatrics, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine/National Clinical Research Center For Chinese Medicine Acupuncture and Moxibustion, Tianjin, China

². Department of Clinical Trial Center, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine/National Clinical Research Center For Chinese Medicine Acupuncture and Moxibustion, Tianjin, China

³. Department of Pediatrics, Xiamen Hospital of Traditional Chinese Medicine, Xiamen, China

⁴. Department of Pediatrics, Taizhou Hospital of Traditional Chinese Medicine, Taizhou, China

⁵. Department of Pediatrics, Shanghai Hospital of Traditional Chinese Medicine, Shanghai, China

⁶. Department of Pediatrics, The First Hospital of Hunan University of Chinese Medicine, Changsha, China

⁷. Department of Pediatrics, The First Affiliated Hospital of Henan University of Chinese Medicine, Zhengzhou, China

⁸. Department of Pediatrics, Hospital of Chengdu University of TCM, Chengdu, China

⁹. Department of Pediatrics, Heilongjiang University of Chinese Medicine, Harbin, China

¹⁰. Department of Pediatrics, Pingxiang Maternal and Child Health Hospital, Pingxiang, China

¹¹. Department of Pediatrics, Affiliated Hospital of Henan Academy of Chinese Medicine, Zhengzhou, China

¹². Department of Pediatrics, Foshan Women and Children Hospital, Foshan, China

¹³. Department of Pediatrics, Changde First People's Hospital, Changde, China

¹⁴. Department of Pediatrics, The First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, China

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Chengliang Zhong, Shengxuan Guo, Yimin Yang, Aizhen Wang, Zheng Xue, Mengqing Wang, Guihua Song, Kun Yang, Hai Wang, Wei Zhong, Ya Gao, Zhigang Liu, Minghui Wang, Yuyan Chen, Xinmin Li, Siyuan Hu. Efficacy and Safety of Xiaoer Chiqiao Qingre Syrup in the Treatment of Pedo-Anemopyretic Cold With Stagnant Syndrome in Children: A Multicenter, Randomized, Double-Blind, Double-Dummy, Parallel, Positive-Controlled, Noninferiority Trial. Journal of Evidence-Based Medicine, 2025, 18(3): e70077 DOI:10.1111/jebm.70077