Clinical Practice Guidelines for Topical NSAIDs in the Treatment of Sports Injuries

Yan Xiong , Yan Liu , Jingbin Zhou , Xiliang Shang , Hongchen He , Guoping Li , Shiyi Chen , Jian Li

Journal of Evidence-Based Medicine ›› 2025, Vol. 18 ›› Issue (1) : e12661

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Journal of Evidence-Based Medicine ›› 2025, Vol. 18 ›› Issue (1) : e12661 DOI: 10.1111/jebm.12661
GUIDELINE

Clinical Practice Guidelines for Topical NSAIDs in the Treatment of Sports Injuries

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Abstract

Topical nonsteroidal anti-inflammatory drugs (NSAIDs) are commonly used to treat sports injuries, but evidence-based medical guidance for their standardized and rational use is lacking. This guideline working group identified clinically important issues, obtained the full opinions of patients and clinical staff, and discussed them with the expert group. Based on evidence from the literature, the “clinical practice guidelines for topical NSAIDs in the treatment of sports injuries” were formulated following the methods and principles of international guidelines. According to these guidelines, 7 clinical concerns were ultimately selected, and 22 recommendationswere formed. These included the status, indications, contraindications, efficacy, combined application, use in special populations, adverse reactions, and countermeasures of topical NSAIDs in the treatment of sports injuries. The purpose of these guidelines is to provide evidence-based recommendations for practitioners in the fields of orthopedics, sports medicine, rehabilitationmedicine, and sports science, as well as other fields, in the treatment of sports injuries to promote more standardized and rational use of topical NSAIDs.

Keywords

clinical practice guidelines / sports injury / topical NSAIDs

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Yan Xiong, Yan Liu, Jingbin Zhou, Xiliang Shang, Hongchen He, Guoping Li, Shiyi Chen, Jian Li. Clinical Practice Guidelines for Topical NSAIDs in the Treatment of Sports Injuries. Journal of Evidence-Based Medicine, 2025, 18(1): e12661 DOI:10.1111/jebm.12661

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