Deciphering unique and shared interactions between the human gut microbiota and oral antidiabetic drugs

Huahui Ren; Zhun Shi; Fangming Yang; Shujie Wang; Fengyi Yuan; Tingting Li; Min Li; Jiahui Zhu; Junhua Li; Kui Wu; Yifei Zhang; Guang Ning; Karsten Kristiansen; Weiqing Wang; Yanyun Gu; Huanzi Zhong

doi:10.1002/imt2.179

iMeta ›› 2024, Vol. 3 ›› Issue (2) :179 DOI: 10.1002/imt2.179

COMMENTARY

Deciphering unique and shared interactions between the human gut microbiota and oral antidiabetic drugs

Huahui Ren ¹^,²
, Zhun Shi ¹
, Fangming Yang ¹
, Shujie Wang ³^,⁴
, Fengyi Yuan ⁵
, Tingting Li ³^,⁴
, Min Li ¹
, Jiahui Zhu ¹
, Junhua Li ¹^,⁶
, Kui Wu ¹^,⁷
, Yifei Zhang ³^,⁴
, Guang Ning ³^,⁴
, Karsten Kristiansen ¹^,²^,^†
, Weiqing Wang ³^,⁴^,^†
, Yanyun Gu ³^,⁴^,^†
, Huanzi Zhong ¹^,^†

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¹. BGI Research, Shenzhen, China

². Department of Biology, Laboratory of Genomics and Molecular Biomedicine, University of Copenhagen, Copenhagen, Denmark

³. Department of Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China

⁴. Shanghai National Clinical Research Center for Metabolic Diseases, Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission of the PR China, Shanghai National Center for Translational Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China

⁵. Department of Endocrinology and Metabolism, Shenzhen People’s Hospital, Shenzhen, China

⁶. Shenzhen Key Laboratory of Unknown Pathogen Identification, BGI Research, Shenzhen, China

⁷. Guangdong Provincial Key Laboratory of Human Disease Genomics, Shenzhen Key Laboratory of Genomics, BGI Research, Shenzhen, China

kk@bio.ku.dk

Wqingw61@163.com

guyanyun@sjtu.edu.cn

zhonghuanzi@genomics.cn

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Huahui Ren, Zhun Shi, Fangming Yang, Shujie Wang, Fengyi Yuan, Tingting Li, Min Li, Jiahui Zhu, Junhua Li, Kui Wu, Yifei Zhang, Guang Ning, Karsten Kristiansen, Weiqing Wang, Yanyun Gu, Huanzi Zhong. Deciphering unique and shared interactions between the human gut microbiota and oral antidiabetic drugs. iMeta, 2024, 3(2): 179 DOI:10.1002/imt2.179