Glucomannan promotes Bacteroides ovatus to improve intestinal barrier function and ameliorate insulin resistance
Qixing Nie , Yonggan Sun , Wenbing Hu , Chunhua Chen , Qiongni Lin , Shaoping Nie
iMeta ›› 2024, Vol. 3 ›› Issue (1) : 163
•Supplementation with glucomannan alleviates insulin resistance. •Glucomannan promotes the growth of Bacteroides ovatus, accompanied by improved intestinal barrier integrity and reduced systemic inflammation. •B. ovatus-derived indoleacetic acid is a key bioactive metabolite that fortifies intestinal barrier function via the activation of intestinal aryl hydrocarbon receptor.
aryl hydrocarbon receptor / B. ovatus / glucomannan / indoleacetic acid
2024 The Authors. iMeta published by John Wiley & Sons Australia, Ltd on behalf of iMeta Science.
/
| 〈 |
|
〉 |
PDF
