Bacmethy: A novel and convenient tool for investigating bacterial DNA methylation pattern and their transcriptional regulation effects

Ji-Hong Liu; Yizhou Zhang; Ning Zhou; Jiale He; Jing Xu; Zhao Cai; Liang Yang; Yang Liu

doi:10.1002/imt2.186

iMeta ›› 2024, Vol. 3 ›› Issue (3) : 186 DOI: 10.1002/imt2.186

METHOD

Bacmethy: A novel and convenient tool for investigating bacterial DNA methylation pattern and their transcriptional regulation effects

Ji-Hong Liu ¹^,²
, Yizhou Zhang ¹^,²
, Ning Zhou ³
, Jiale He ¹^,²
, Jing Xu ¹
, Zhao Cai ²
, Liang Yang ²^,⁴^,^†
, Yang Liu ¹^,^†

Author information +

History +

PDF

Abstract

•Bacmethy tool provides a one-stop analysis and visualization pipeline for effectively characterizing bacterial DNA methylation modification features and predicting the regulation patterns.

•Bacmethy offers both a local run function and an online interface analysis service, providing significant convenience for researchers without coding abilities.

•Bacmethy provides useful information for decoding the underlying molecular mechanisms of how DNA methylation regulates bacterial cellular and physiological functions.

Keywords

bacteria / DNA methylation / SMRT-seq / transcriptional regulation / undermethylation

Cite this article

Download citation ▾

Ji-Hong Liu, Yizhou Zhang, Ning Zhou, Jiale He, Jing Xu, Zhao Cai, Liang Yang, Yang Liu. Bacmethy: A novel and convenient tool for investigating bacterial DNA methylation pattern and their transcriptional regulation effects. iMeta, 2024, 3(3): 186 DOI:10.1002/imt2.186