Clostridium butyricum and carbohydrate active enzymes contribute to the reduced fat deposition in pigs

Lingyan Ma , Shiyu Tao , Tongxing Song , Wentao Lyu , Ying Li , Wen Wang , Qicheng Shen , Yan Ni , Jiang Zhu , Jiangchao Zhao , Hua Yang , Yingping Xiao

iMeta ›› 2024, Vol. 3 ›› Issue (1) : 160

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iMeta ›› 2024, Vol. 3 ›› Issue (1) : 160 DOI: 10.1002/imt2.160
RESEARCH ARTICLE

Clostridium butyricum and carbohydrate active enzymes contribute to the reduced fat deposition in pigs

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Abstract

•Significant differences in microbial composition and potential functional capacity among different gut locations were found in Jinhua pigs with distinct fatness phenotypes.

•Jinhua pigs with lower fatness exhibited higher levels of short-chain fatty acids in the colon, highlighting their enhanced carbohydrate fermentation capacity.

Clostridium butyricum might be a representative bacterial species from Jinhua pigs with lower fatness, and a significantly higher percentage of its genome was dedicated to CAZyme glycoside hydrolase family 13 (GH13).

•Isolated C. butyricum alleviated fat accumulation and increased the enrichment of GH13 in obese mice.

Keywords

CAZymes / Clostridium butyricum / fatness / gut microbiota / Jinhua pigs / metagenomics

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Lingyan Ma, Shiyu Tao, Tongxing Song, Wentao Lyu, Ying Li, Wen Wang, Qicheng Shen, Yan Ni, Jiang Zhu, Jiangchao Zhao, Hua Yang, Yingping Xiao. Clostridium butyricum and carbohydrate active enzymes contribute to the reduced fat deposition in pigs. iMeta, 2024, 3(1): 160 DOI:10.1002/imt2.160

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2024 The Authors. iMeta published by John Wiley & Sons Australia, Ltd on behalf of iMeta Science.

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