Recent advances in the characterization of essential genes and development of a database of essential genes
Ya-Ting Liang , Hao Luo , Yan Lin , Feng Gao
iMeta ›› 2024, Vol. 3 ›› Issue (1) : 157
Recent advances in the characterization of essential genes and development of a database of essential genes
•Essential genes are crucial for organism survival and development, which have been identified using various experimental methods across different organisms, providing valuable resources for studying their characteristics and developing predictive algorithms. •The database of essential genes (DEG) collects experimental results on essential genes and serves as a widely used resource for studying them. It enables quick access to essential gene information for specific species and has applications in essential gene analysis, prediction, drug and vaccine design, and artificial genome construction. •The definition of essential genes is context-dependent, not a simple binary classification. Integrating different experimental results of essential genes is challenging but offers opportunities to explore gene interaction mechanisms.
database of essential genes / drug and vaccine design / essential gene / gene essentiality prediction / genome design
2024 The Authors. iMeta published by John Wiley & Sons Australia, Ltd on behalf of iMeta Science.
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