A haplotype-resolved genome assembly of seed hemp (Cannabis sativa) and analysis of Y chromosome divergence from the X

Huawei Wei; Zuqing Yang; Lingling Zhuang; Xueqing Pan; Haifeng Jia; Shaolian Jiang; Qin Li; Jiantang Xu; Aifen Tao; Pingping Fang; Jianmin Qi; Ray Ming; Liwu Zhang

doi:10.1093/hr/uhaf268

Horticulture Research ›› 2026, Vol. 13 ›› Issue (1) :268 DOI: 10.1093/hr/uhaf268

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A haplotype-resolved genome assembly of seed hemp (Cannabis sativa) and analysis of Y chromosome divergence from the X

Huawei Wei ¹^,²^,³^,⁴
, Zuqing Yang ¹^,²^,³
, Lingling Zhuang ¹^,²^,³
, Xueqing Pan ¹^,²^,³
, Haifeng Jia ³
, Shaolian Jiang ¹^,²^,³
, Qin Li ¹^,²^,³
, Jiantang Xu ¹^,²
, Aifen Tao ¹^,²
, Pingping Fang ¹^,²
, Jianmin Qi ¹^,²
, Ray Ming ³^,⁵^,^‡
, Liwu Zhang ¹^,²^,³^,^*

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Huawei Wei, Zuqing Yang, Lingling Zhuang, Xueqing Pan, Haifeng Jia, Shaolian Jiang, Qin Li, Jiantang Xu, Aifen Tao, Pingping Fang, Jianmin Qi, Ray Ming, Liwu Zhang. A haplotype-resolved genome assembly of seed hemp (Cannabis sativa) and analysis of Y chromosome divergence from the X. Horticulture Research, 2026, 13(1): 268 DOI:10.1093/hr/uhaf268

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Acknowledgements

This work was supported by funds from the Natural Science Foundation of China (32472219), Fujian Provincial Natural Science Foundation (2023J01443), the Science and Technology Innovation Project of Fujian Agriculture and Forestry University (KFB23001, KFB24080), and China Agriculture Research System of MOF and MARA (CARS-16). This work was supported by the platforms of Key Laboratory of Ministry of Agriculture and Rural Affairs for Biological Breeding of Fujian and Taiwan Crops, and Fujian International Science and Technology Cooperation Base for Genetic Breeding and Multiple Utilization Development of Southern Economic Crops.

Authors contributions

R.M. and L.Z. jointly supervised the work. H.W. and H.J., performed sequencing, assembly and genome annotation. Z.Y., L.Z., X.P., S.J., Q.L., J.X., A.T., P.F., and J.Q. contributed to data analysis. H.W. wrote the manuscript. R.M. and L.Z. revised the manuscript. L.Z. conceived the project. We thank Hongmei Kang at Shanxi Agricultural University for providing the seeds of ‘yushe’.

Data availability

The seed hemp genomic data are available in the China National Center for Bioinformation under accession number PRJCA026839. Furthermore, the supplementary documents in the manuscript can be found at the following website: https://www.researchsquare.com/article/rs-6374740/v1.

Conflicts of interest statement

The authors declare no competing financial interests.

References

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