PDF
Abstract
Microwave coagulation therapy (MCT) is a relatively new method of tumor ablation compared to other minimally invasive local therapies for hepatocellular carcinoma (HCC). It is a thermal ablation modality based on the application of heat, potentially leading to larger ablation zones. In recent years, there is a steady increase in the application of this modality to the treatment of HCC because it offers several advantages in the management of tumors larger than 3 cm in diameter. This article reviews the advances in MCT for the treatment of HCC in recent years including its brief history, basic principles, main technical parameters, safety issues, current status in clinical application, limitations, and future perspectives.
Keywords
Coagulation
/
hepatocellular carcinoma
/
microwave
/
treatment
Cite this article
Download citation ▾
Yong-Song Guan.
Microwave coagulation therapy of hepatocellular carcinoma.
Hepatoma Research, 2015, 1: 159-64 DOI:10.4103/2394-5079.164648
| [1] |
Inoue Y,Hazumi M,Okamura T,Tomaru T.Cryogenic infrared filter made of alumina for use at millimeter wavelength..Appl Opt2014;53:1727-33
|
| [2] |
Lubner MG,Ziemlewicz TJ,Lee FTJr.Microwave ablation of hepatic malignancy..Semin Intervent Radiol2013;30:56-66 PMCID:PMC3700788
|
| [3] |
Huo X,Ghovanloo M.Radiation characterization of an intra-oral wireless device at multiple ISM bands: 433 MHZ, 915 MHZ, and 2.42 GHz..Conf Proc IEEE Eng Med Biol Soc2010;2010:1425-8
|
| [4] |
Zhou W,Pan H,Jiang Y,Ling L,Wang S.Comparison of ablation zones among different tissues using 2450-MHz cooled-shaft microwave antenna: results in ex vivo porcine models..PLoS One2013;8:e71873 PMCID:PMC3741232
|
| [5] |
Blechacz B.Hepatocellular carcinoma biology..Recent Results Cancer Res2013;190:1-20
|
| [6] |
Li D,Golas BJ,Madoff DC.Minimally invasive local therapies for liver cancer..Cancer Biol Med2014;11:217-36 PMCID:PMC4296086
|
| [7] |
Simon CJ,Mayo-Smith WW.Microwave ablation: principles and applications..Radiographics2005;25:Suppl 1S69-83
|
| [8] |
Yanaga K.Current status of hepatic resection for hepatocellular carcinoma..J Gastroenterol2004;39:919-26
|
| [9] |
Inokuchi R,Ikeda K,Asayama T,Umehara H.Percutaneous microwave coagulation therapy for hepatocellular carcinoma: increased coagulation diameter using a new electrode and microwave generator..Oncol Rep2010;24:621-7
|
| [10] |
Segawa T,Furui J,Tsunoda T.Operative results in 143 patients with hepatocellular carcinoma..World J Surg1993;17:663-7; discussion 668
|
| [11] |
Onizuka Y.Development of a microwave-induced hyperthermia system with multiple applicators..Kurume Med J1989;36:189-97
|
| [12] |
Matsuda T,Tanaka Y,Nishimura Y,Takahashi M,Fuwa N.Clinical research into hyperthermia treatment of cancer using a 430 MHz microwave heating system with a lens applicator..Int J Hyperthermia1991;7:425-40
|
| [13] |
Itoh S,Kawanaka H,Kawasaki K,Korenaga D.Efficacy of surgical microwave therapy in patients with unresectable hepatocellular carcinoma..Ann Surg Oncol2011;18:3650-6
|
| [14] |
Matsuda T.The present status of hyperthermia in Japan..Ann Acad Med Singapore1996;25:420-4
|
| [15] |
Meyer JL.The clinical efficacy of localized hyperthermia..Cancer Res1984;44:s4745-51
|
| [16] |
Frérart F,Rath G,Meqor A,Jordan BF,Noël A,Gallez B.The acidic tumor microenvironment promotes the reconversion of nitrite into nitric oxide: towards a new and safe radiosensitizing strategy..Clin Cancer Res2008;14:2768-74
|
| [17] |
Sommer CM,Sommer WO,Wolf MB,Meinzer HP,Stampfl U,Pereira PL.Optimisation of the coagulation zone for thermal ablation procedures: a theoretical approach with considerations for practical use..Int J Hyperthermia2013;29:620-8
|
| [18] |
Nan Q,Fan Z,Zeng Y.Analysis to a critical state of thermal field in microwave ablation of liver cancer influenced by large vessels..Int J Hyperthermia2010;26:34-8
|
| [19] |
Matylevitch NP,Mata JR,Lawlor DF,Bowman PD.Apoptosis and accidental cell death in cultured human keratinocytes after thermal injury..Am J Pathol1998;153:567-77
|
| [20] |
Spliethoff JW,Evers DJ,Prevoo W.Monitoring of tumor radio frequency ablation using derivative spectroscopy..J Biomed Opt2014;19:97004
|
| [21] |
Szmigielski S,Sokolska G,Zielinski H.Effects of local prostatic hyperthermia on human NK and T cell function..Int J Hyperthermia1991;7:869-80
|
| [22] |
Liang P.Microwave ablation of hepatocellular carcinoma..Oncology2007;72:Suppl 1124-31
|
| [23] |
Zastrow E,Van Veen BD.3D computational study of non-invasive patient-specific microwave hyperthermia treatment of breast cancer..Phys Med Biol2010;55:3611-29 PMCID:PMC3159563
|
| [24] |
Guan YS.Interventional treatments for hepatocellular carcinoma..Hepatobiliary Pancreat Dis Int2006;5:495-500
|
| [25] |
Lu Y,Li L.Numerical study on thermal field of microwave ablation with water-cooled antenna..Int J Hyperthermia2009;25:108-15
|
| [26] |
Lopresto V,Cavagnaro M.Experimental characterisation of the thermal lesion induced by microwave ablation..Int J Hyperthermia2014;30:110-8
|
| [27] |
Liu DQ,Tan JF,Zhou ZX.Microwave coagulation at different temperatures for hepatocellular carcinoma management: efficacy evaluation by enzyme histochemical staining..Nan Fang Yi Ke Da Xue Xue Bao2006;26:1149-51
|
| [28] |
Lubner MG,Andreano A,Lee FTJr.High-powered microwave ablation with a small-gauge, gas-cooled antenna: initial ex vivo and in vivo results..J Vasc Interv Radiol2012;23:405-11 PMCID:PMC3289683
|
| [29] |
Jovanović-Ignjatić Z.A review of current research in microwave resonance therapy: novel opportunities in medical treatment..Acupunct Electrother Res1999;24:105-25
|
| [30] |
Shi RJ,Wang QL.The application of microwave coagulating instrument in otolaryngology and stomatology (report of 157 cases)..Shanghai Kou Qiang Yi Xue2000;9:58-9
|
| [31] |
Jiao D,Zhang Y,Li C,Zhang L,Wu P,Duan G.Microwave ablation treatment of liver cancer with 2,450-MHz cooled-shaft antenna: an experimental and clinical study..J Cancer Res Clin Oncol2010;136:1507-16
|
| [32] |
Sommer CM,Koch V,Holzschuh M,Gehrig T,Nickel F,Zelzer S,Stampfl U,Radeleff BA.Microwave ablation of porcine kidneys in vivo: effect of two different ablation modes ("temperature control" and "power control") on procedural outcome..Cardiovasc Intervent Radiol2012;35:653-60
|
| [33] |
Crocetti L,Faviana P,Della Pina C,Fontanini G.Thermal ablation of lung tissue: in vivo experimental comparison of microwave and radiofrequency..Cardiovasc Intervent Radiol2010;33:818-27
|
| [34] |
Haen SP,Salih HR,Gouttefangeas C.More than just tumor destruction: immunomodulation by thermal ablation of cancer..Clin Dev Immunol2011;2011:160250
|
| [35] |
Sofocleous CT,Petre EN."How we do it" - a practical approach to hepatic metastases ablation techniques..Tech Vasc Interv Radiol2013;16:219-29
|
| [36] |
Han XJ,Liang P,Yu DJ.Local cellular immune response induced by ultrasound-guided tumor bed superantigen injection after percutaneous microwave coagulation therapy for liver cancer..Zhonghua Zhong Liu Za Zhi2009;31:602-6(in Chinese)
|
| [37] |
Nie Y,Mou Y,Xu Z,Wang W,Wang T.Low frequency magnetic fields enhance antitumor immune response against mouse H22 hepatocellular carcinoma..PLoS One2013;8:e72411 PMCID:PMC3835892
|
| [38] |
Gravante G,Ong SL,Lloyd DM.Immunoregulatory effects of liver ablation therapies for the treatment of primary and metastatic liver malignancies..Liver Int2009;29:18-24
|
| [39] |
Paulson KG,Simonson WT,Thibodeau RM,Pietromonaco S,Warton EM,Nghiem P.CD8+ lymphocyte intratumoral infiltration as a stage-independent predictor of Merkel cell carcinoma survival: a population-based study..Am J Clin Pathol2014;142:452-8 PMCID:PMC4174450
|
| [40] |
Wolf FJ,Ng T.Intraoperative microwave ablation of pulmonary malignancies with tumor permittivity feedback control: ablation and resection study in 10 consecutive patients..Radiology2012;262:353-60
|
| [41] |
Di Vece F,Ermili F,Sartori S.Coagulation areas produced by cool-tip radiofrequency ablation and microwave ablation using a device to decrease back-heating effects: a prospective pilot study..Cardiovasc Intervent Radiol2014;37:723-9
|
| [42] |
Jacobsen S.Improved detectability in medical microwave radio-thermometers as obtained by active antennas..IEEE Trans Biomed Eng2008;55:2778-85
|
| [43] |
Phasukkit P,Sangworasil M.Finite-element analysis and in vitro experiments of placement configurations using triple antennas in microwavehepatic ablation..IEEE Trans Biomed Eng2009;56:2564-72
|
| [44] |
Chiang J,Bedoya M.A dual-slot microwave antenna for more spherical ablation zones: ex vivo and in vivo validation..Radiology2013;268:382-9 PMCID:PMC3721053
|
| [45] |
Haines DE.Current and future modalities of catheter ablation for the treatment of cardiac arrhythmias..J Invasive Cardiol1992;4:291-9
|
| [46] |
Chou CK.Evaluation of microwave hyperthermia applicators..Bioelectromagnetics1992;13:581-97
|
| [47] |
Sneed PK,Stauffer PR,Smith V.Interstitial microwave hyperthermia in a canine brain model..Int J Radiat Oncol Biol Phys1986;12:1887-97
|
| [48] |
Liu FY,Liang P,Zhou P.Comparison of percutaneous 915 MHz microwave ablation and 2450 MHz microwave ablation in large hepatocellular carcinoma..Int J Hyperthermia2010;26:448-55
|
| [49] |
Keserci BM,Suzuki K,Okada A,Kuroda K.Near-real-time feedback control system for liver thermal ablations based on self-referenced temperature imaging..Eur J Radiol2006;59:175-82
|
| [50] |
Kurumi Y,Naka S,Shimizu T,Endo Y.MR-guided microwave ablation for malignancies..Int J Clin Oncol2007;12:85-93
|
| [51] |
Umehara H,Inokuchi R,Kawamura R,Ikeda K.Microwave coagulation using a perfusion microwave electrode: Preliminary experimental study using ex vivo and in vivo liver..Exp Ther Med2012;3:214-20 PMCID:PMC3438625
|
| [52] |
Gazzera C,Faletti R,Gobbi F,Gandini G.Role of paravertebral block anaesthesia during percutaneous transhepatic thermoablation..Radiol Med2014;119:549-57
|
| [53] |
Shiina S.Image-guided percutaneous ablation therapies for hepatocellular carcinoma..J Gastroenterol2009;44:Suppl 19122-31
|
| [54] |
Kim YS,Rhim H.Ablation of hepatocellular carcinoma..Best Pract Res Clin Gastroenterol2014;28:897-908
|
| [55] |
Takami Y,Wada Y.Evaluation of intraoperative microwave coagulo-necrotic therapy (MCN) for hepatocellular carcinoma: a single center experience of 719 consecutive cases..J Hepatobiliary Pancreat Sci2013;20:332-41 PMCID:PMC3590403
|
| [56] |
Andreano A,Franza E,Sironi S,Meloni MF.Percutaneous microwave ablation of hepatic tumors: prospective evaluation of postablation syndrome and postprocedural pain..J Vasc Interv Radiol2014;25:97-105.e1-2
|
| [57] |
Kosugi C,Ishii H,Yoshino M,Konishi M,Inoue K.Needle tract implantation of hepatocellular carcinoma and pancreatic carcinoma after ultrasound-guided percutaneous puncture: clinical and pathologic characteristics and the treatment of needle tract implantation..World J Surg2004;28:29-32
|
| [58] |
Yu F,Yan ZL,Li J,Cong WM,Shen F.Clinical study of 169 patients with hepatic angiomyolipoma..Zhonghua Wai Ke Za Zhi2010;48:1621-4(in Chinese)
|
| [59] |
Sato M,Watanabe Y,Kohtani T,Kawachi K,Sugita A.Generalized intraperitoneal seeding of hepatocellular carcinoma after microwave coagulation therapy: a case report..Hepatogastroenterology1999;46:2561-4
|
| [60] |
Takahashi Y,Shimano T,Niinobu T,Takami M,Ishida T.A case report of intra-thoracic biliary fistula after percutaneous microwave coagulation therapy..Gan To Kagaku Ryoho2000;27:1850-3(in Japanese)
|
| [61] |
Ajisaka H.Acute respiratory distress syndrome is a serious complication of microwave coagulation therapy for liver tumors..Am J Surg2005;189:730-3
|
| [62] |
Ding J,Liu J,Wang F,Du Z.Complications of thermal ablation of hepatic tumours: comparison of radiofrequency and microwave ablative techniques..Clin Radiol2013;68:608-15
|
| [63] |
Zhang H,Huang Z,Song Z.Computed tomography-guided percutaneous microwave ablation for diaphragm-abutting liver tumors: assessments of safety and short-term therapeutic efficacies..Zhonghua Yi Xue Za Zhi2014;94:1313-7(in Chinese)
|
| [64] |
Takao Y,Mamada Y,Bando K.Transcatheter hepatic arterial embolization followed by microwave ablation for hemobilia from hepatocellular carcinoma..J Nippon Med Sch2008;75:284-8
|
| [65] |
Cohen GS.Multidisciplinary management of hepatocellular carcinoma: a model for therapy..J Multidiscip Healthc2013;6:189-95 PMCID:PMC3656893
|
| [66] |
Pan WD,Nan L,Liu B,Deng MH.Ultrasound-guided percutaneous microwave coagulation therapy with a "cooled-tip needle" for the treatment of hepatocellular carcinoma adjacent to the gallbladder..Dig Dis Sci2010;55:2664-9
|