Hepatocellular carcinoma in elderly patients: a concise review on systemic therapy with sorafenib

Lombardi Giuseppe , Vitale Alessandro , Sara Lonardi , Bellu Luisa , Pambuku Ardi , Marsico Valentina , Crivellari Gino , Aliberti Camillo , Cillo Umberto , Zagonel Vittorina

Hepatoma Research ›› 2015, Vol. 1 : 58 -62.

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Hepatoma Research ›› 2015, Vol. 1:58 -62. DOI: 10.4103/2394-5079.157695
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Hepatocellular carcinoma in elderly patients: a concise review on systemic therapy with sorafenib

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Abstract

The treatment of hepatocellular carcinoma (HCC) in elderly patients is unclear. In particular, the efficacy and safety of sorafenib as a systemic treatment in these patients is still under debate. We performed a concise review of sorafenib therapy in this population. However, it is important to make any decisions on treatment for elderly patients with HCC through a multidisciplinary team that includes experts in the liver disease. Patients with good clinical conditions should be treated with sorafenib.

Keywords

Hepatocellular carcinoma / sorafenib / treatment / chemotherapy / elderly patients

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Lombardi Giuseppe, Vitale Alessandro, Sara Lonardi, Bellu Luisa, Pambuku Ardi, Marsico Valentina, Crivellari Gino, Aliberti Camillo, Cillo Umberto, Zagonel Vittorina. Hepatocellular carcinoma in elderly patients: a concise review on systemic therapy with sorafenib. Hepatoma Research, 2015, 1: 58-62 DOI:10.4103/2394-5079.157695

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