Impact of gut microbiome on immunotherapy resistance in hepatocellular carcinoma: a review article

Aun R. Shah , Sandeep Mukherjee

Hepatoma Research ›› 2024, Vol. 10 : 48

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Hepatoma Research ›› 2024, Vol. 10:48 DOI: 10.20517/2394-5079.2024.76
Review

Impact of gut microbiome on immunotherapy resistance in hepatocellular carcinoma: a review article

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Abstract

This article reviews the interactions between gut microbiota and cancer immunotherapies and discusses microbiota-based patient stratification strategies such as the prediction of response and the early recognition of toxic events. Additionally, it explores the emerging potential of microbiotherapy to enhance anti-neoplastic efficacy and alleviate toxicity, with the ultimate goal of developing personalized treatment regimens for patients with hepatocellular carcinoma (HCC).

Keywords

Hepatocellular carcinoma / HCC / immunotherapy / microbiota / microbiome

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Aun R. Shah, Sandeep Mukherjee. Impact of gut microbiome on immunotherapy resistance in hepatocellular carcinoma: a review article. Hepatoma Research, 2024, 10: 48 DOI:10.20517/2394-5079.2024.76

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