From PVE to HVE to fully laparoscopic rescue ALPPS: a case report of multidisciplinary management of giant HCC

Valentina Malerba , Andrea Benedetti Cacciaguerra , Giuseppe Zimmitti , Alberto Manzoni , Claudio Sallemi , Lorenzo Monfardini , Massimo Graffeo , Claudio Bnà , Giuseppe Natalini , Alberto Zaniboni , Maria Cristina Montresor , Claudio Codignola , Marco Garatti , Mohammed Abu Hilal

Hepatoma Research ›› 2021, Vol. 7 : 19

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Hepatoma Research ›› 2021, Vol. 7:19 DOI: 10.20517/2394-5079.2020.131
Case Report
Case Report

From PVE to HVE to fully laparoscopic rescue ALPPS: a case report of multidisciplinary management of giant HCC

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Abstract

Different strategies have been used to induce preoperative liver hypertrophy and reduce the risk of postoperative liver failure. Those have included both radiological-interventional and surgical strategies, such as portal and hepatic vein embolization, 2-stage hepatectomy and associated liver partition with portal vein ligation for staged hepatectomy (ALPPS). Herein, we describe the case of a patient with a large right liver hepatocellular carcinoma not amenable to liver transplantation, with HBV-related chronic hepatitis and a small future liver remnant (FLR), who underwent a multistep approach to ensure a safe major laparoscopic resection with an adequate FLR.

Keywords

Portal vein embolization / hepatic vein embolization / rescue ALPPS / laparoscopic surgery / hepatectomy / hepatocellular carcinoma

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Valentina Malerba, Andrea Benedetti Cacciaguerra, Giuseppe Zimmitti, Alberto Manzoni, Claudio Sallemi, Lorenzo Monfardini, Massimo Graffeo, Claudio Bnà, Giuseppe Natalini, Alberto Zaniboni, Maria Cristina Montresor, Claudio Codignola, Marco Garatti, Mohammed Abu Hilal. From PVE to HVE to fully laparoscopic rescue ALPPS: a case report of multidisciplinary management of giant HCC. Hepatoma Research, 2021, 7: 19 DOI:10.20517/2394-5079.2020.131

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References

[1]

Kishi Y,Chun YS.Three hundred and one consecutive extended right hepatectomies: evaluation of outcome based on systematic liver volumetry..Ann Surg2009;250:540-8

[2]

Lang H,Brokalaki EI.Left hepatic trisectionectomy for hepatobiliary malignancies..J Am Coll Surg2006;203:311-21

[3]

Adam R,Ariche A.Five-year survival following hepatic resection after neoadjuvant therapy for nonresectable colorectal..Ann Surg Oncol2001;8:347-53

[4]

Ge PL,Mao YL.Advances in preoperative assessment of liver function..Hepatobiliary Pancreat Dis Int2014;13:361-70

[5]

Ren Z,Zhu S.Indocyanine green retention test avoiding liver failure after hepatectomy for hepatolithiasis..Hepatogastroenterology2012;59:782-4

[6]

Wakabayashi H,Maeba T.Evaluation of liver function for the application of preoperative portal vein embolization on major hepatic resection..Hepatogastroenterology2002;49:1048-52

[7]

Vauthey JN,Abdalla EK.Pretreatment assessment of hepatocellular carcinoma: expert consensus statement..HPB (Oxford)2010;12:289-99 PMCID:PMC2951814

[8]

May BJ.Portal vein embolization: rationale, technique, and current application..Semin Intervent Radiol2012;29:81-9 PMCID:PMC3444878

[9]

van Lienden KP,de Graaf W.Portal vein embolization before liver resection: a systematic review..Cardiovasc Intervent Radiol2013;36:25-34 PMCID:PMC3549243

[10]

Azoulay D,Krissat J.Percutaneous portal vein embolization increases the feasibility and safety of major liver resection for hepatocellular carcinoma in injured liver..Ann Surg2000;232:665-72 PMCID:PMC1421241

[11]

Okabe H,Ishiko T.Preoperative portal vein embolization (PVE) for patients with hepatocellular carcinoma can improve resectability and may improve disease-free survival..J Surg Oncol2011;104:641-6

[12]

Schnitzbauer AA,Goessmann H.Right portal vein ligation combined with in situ splitting induces rapid left lateral liver lobe hypertrophy enabling 2-staged extended right hepatic resection in small-for-size settings..Ann Surg2012;255:405-14

[13]

Lang H,Schlitt HJ.10th Anniversary of ALPPS-Lessons Learned and quo Vadis..Ann Surg2019;269:114-9

[14]

Niekamp AS,Mahvash A.Hepatic vein embolization after portal vein embolization to induce additional liver hypertrophy in patients with metastatic colorectal carcinoma..Eur Radiol2020;30:3862-8

[15]

Wong MC,Goggins WB.International incidence and mortality trends of liver cancer: a global profile..Sci Rep2017;7:45846 PMCID:PMC5374459

[16]

Poon RT.Optimal initial treatment for early hepatocellular carcinoma in patients with preserved liver function: transplantation or resection?.Ann Surg Oncol2007;14:541-7

[17]

Pulitano C,Joseph D,Sandroussi C.Preoperative assessment of postoperative liver function: the importance of residual liver volume..J Surg Oncol2014;110:445-50

[18]

Tustumi F,Coelho FF.Preoperative strategies to improve resectability for hepatocellular carcinoma: a systematic review and meta-analysis..HPB (Oxford)2018;20:1109-18

[19]

Hwang S,Ko GY.Sequential preoperative ipsilateral hepatic vein embolization after portal vein embolization to induce further liver regeneration in patients with hepatobiliary malignancy..Ann Surg2009;249:608-16

[20]

Abdalla EK,Vauthey JN.Portal vein embolization: rationale, technique and future prospects..Br J Surg2001;88:165-75

[21]

Görgec B,Al-Jarrah R.Surgical technique and clinical results of one- or two-stage laparoscopic right hemihepatectomy after portal vein embolization in patients with initially unresectable colorectal liver metastases: A case series..Int J Surg2020;77:69-75

[22]

Jain G,Mohammed MM.“Stretching the limits of laparoscopic surgery”: two-stage laparoscopic liver resection..J Laparoendosc Adv Surg Tech A2010;20:51-4

[23]

Widmann WD,Greenspan RH.The effects of hepatic vein occlusions..Am J Pathol1962;41:439-54 PMCID:PMC1949661

[24]

Hwang S,Ko GY.Preoperative Sequential Portal and Hepatic Vein Embolization in Patients with Hepatobiliary Malignancy..World J Surg2015;39:2990-8

[25]

van Lienden KP,Rietkerk M.Short-term effects of combined hepatic vein embolization and portal vein embolization for the induction of liver regeneration in a rabbit model..J Vasc Interv Radiol2012;23:962-7

[26]

Schadde E,Robles-Campos R.Early survival and safety of ALPPS: first report of the International ALPPS Registry..Ann Surg2014;260:829-36discussion 836-8

[27]

Dokmak S.Which limits to the “ALPPS” approach?.Ann Surg2012;256:e6

[28]

de Santibañes E.Playing Play-Doh to prevent postoperative liver failure: the “ALPPS” approach..Ann Surg2012;255:415-7

[29]

Chan KS,Shelat VG.Associated liver partition and portal vein ligation for staged hepatectomy: a review..Transl Gastroenterol Hepatol2020;5:37 PMCID:PMC7063517

[30]

Sparrelid E,Tzortzakakis A.Dynamic Evaluation of Liver Volume and Function in Associating Liver Partition and Portal Vein Ligation for Staged Hepatectomy..J Gastrointest Surg2017;21:967-74 PMCID:PMC5443865

[31]

Abu Hilal M,Abu Salameh M.Oncological efficiency analysis of laparoscopic liver resection for primary and metastatic cancer: a single-center UK experience..Arch Surg2012;147:42-8

[32]

Wakabayashi G,Geller DA.Recommendations for laparoscopic liver resection: a report from the second international consensus conference held in Morioka..Ann Surg2015;261:619-29

[33]

Cipriani F,Rawashdeh M.Laparoscopic Parenchymal-Sparing Resections for Nonperipheral Liver Lesions, the Diamond Technique: Technical Aspects, Clinical Outcomes, and Oncologic Efficiency..J Am Coll Surg2015;221:265-72

[34]

Ciria R,Geller DA,Wakabayashi G.Comparative Short-term Benefits of Laparoscopic Liver Resection: 9000 Cases and Climbing..Ann Surg2016;263:761-77

[35]

Abu Hilal M,Dagher I.The Southampton Consensus Guidelines for Laparoscopic Liver Surgery: From Indication to Implementation..Ann Surg2018;268:11-8

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