Hepatic resection for hepatocellular carcinoma

Shun Yamaguchi , Taichiro Kosaka , Susumu Eguchi

Hepatoma Research ›› 2018, Vol. 4 : 50

PDF
Hepatoma Research ›› 2018, Vol. 4:50 DOI: 10.20517/2394-5079.2018.68
Review
Review

Hepatic resection for hepatocellular carcinoma

Author information +
History +
PDF

Abstract

Hepatic resection has become the standard treatment of primary liver cancer. Indications for hepatic resection in patients with hepatocellular carcinoma (HCC) vary greatly between Japan and other countries because the clinical practice guidelines for HCC defined by the Japan Society of Hepatology differ from the EASL-EORTC clinical practice guidelines. Hepatic resection is not recommended as a treatment for the patients at Barcelona Clinic Liver Cancer (BCLC) stage B. Otherwise, there are many surgeons/clinicians who believe that not all HCC patients at BCLC stage B should be excluded from an indication for hepatectomy because many reports showed good prognosis after hepatic resection for HCC patients over BCLC stage B. The survival rate is expected to increase with better outcomes of hepatectomy in the future. This paper has described indications for hepatectomy for patients with HCC through comparison of domestic guidelines with overseas guidelines, focusing on their differences.

Keywords

Hepatic resection / hepatocellular carcinoma / guidelines

Cite this article

Download citation ▾
Shun Yamaguchi, Taichiro Kosaka, Susumu Eguchi. Hepatic resection for hepatocellular carcinoma. Hepatoma Research, 2018, 4: 50 DOI:10.20517/2394-5079.2018.68

登录浏览全文

4963

注册一个新账户 忘记密码

References

[1]

Kudo M,Izumi N,Kadoya M,Okusaka T,Tsuchiya K,Hiraoka A,Ogasawara S,Minami T.JSH consensus-based clinical practice guidelines for the management of hepatocellular carcinoma: 2014 update by the Liver Cancer Study Group of Japan.Liver Cancer2014;3:458-68 PMCID:PMC4531423

[2]

European Association for the Study of the Liver.EASL-EORTC clinical practice guidelines: management of hepatocellular carcinoma.J Hepatol2012;56:908-43

[3]

Pugh RN,Dawson JL,Williams R.Transection of the oesophagus for bleeding oesophageal varices.Br J Surg1973;60:646-9

[4]

Takada Y,Ueda M,Haga H,Ogawa K,Oike F,Uemoto S.Living donor liver transplantation for patients with HCC exceeding the Milan criteria: a proposal of expanded criteria.Dig Dis2007;25:299-302

[5]

Todo S,Japanese Study Group on Organ Transplantation..Living donor liver transplantation for adult patients with hepatocellular carcinoma: experience in Japan.Ann Surg2004;240:451-9 PMCID:PMC1356435

[6]

Liver Cancer Study Group of Japan.The general rules for the clinical and pathological study of primary liver cancer, 6th Japanese ed.Tokyo: Kanehara-Shuppan;2015;

[7]

Fan ST,Lo CM,Wong J.Hospital mortality of major hepatectomy for hepatocellular carcinoma associated with cirrhosis.Arch Surg1995;130:198-203

[8]

Yamanaka N,Oriyama T,Furukawa K,Tanaka T.A prediction scoring system to select the surgical treatment of liver cancer.Further refinement based on 10 years of use. Ann Surg1994;219:342-6 PMCID:PMC1243149

[9]

Miyagawa S,Kawasaki S.Criteria for safe hepatic resection.Am J Surg1995;169:589-94

[10]

Kwon AH,Uetsuji S,Matsui Y.Preoperative determination of the surgical procedure for hepatectomy using technetium-99m-galactosyl human serum albumin (99mTc-GSA) liver scintigraphy.Hepatology1997;25:426-9

[11]

Kamohara Y,Hidaka M,Kanematsu T.99mTc-Galactosyl sialyl albumin (GSA) scintigram adjusts hepatic resection range in ICG based estimation.Hepatogastroenterology2011;58:2058-61

[12]

Hayashi H,Okabe H,Nakagawa S,Nitta H,Ishiko T.Functional assessment versus conventional volumetric assessment in the prediction of operative outcomes after major hepatectomy.Surgery2015;157:20-6

[13]

Lin CT,Chen TW,Chan DC,Hsieh TY,Kuo SM,Hsieh CB.Comparing hepatic resection and transarterial chemoembolization for Barcelona Clinic Liver Cancer (BCLC) stage B hepatocellular carcionoma: change for treatment of choice?.World J Surg2010;34:2155-61

[14]

Wang JH,Hu TH,Kee KM,Chen CL,Huang YJ.The efficacy of treatment schedules according to Barcelona Clinic Liver Cancer staging for hepatocellular carcinoma - survival analysis of 3892 patients.Eur J Cancer2008;44:1000-6

[15]

Zhong JH,Gong WF,Ma L,Peng T,Li LQ.Hepatic resection associated with good survival for selected patients with intermediate and advanced-stage hepatocellular carcinoma.Ann Surg2014;260:329-40

[16]

Torzilli G,Kokudo N,Capussotti L,Vauthey JN,De Santibanes E,Morenghi E.A snapshot of the effective indications and results of surgery for hepatocellular carcinoma in tertiary referral centers: is it adherent to the EASL/AASLD recommendations?: an observational study of the HCC East-West study group.Ann Surg2013;257:929-37

[17]

Ho MC,Tsang YM,Chen DS,Chen CH.Liver resection improves the survival of patients with multiple hepatocellular carcinomas.Ann Surg Oncol2009;16:848-55

[18]

Hasegawa K,Makuuchi M,Ichida T,Ku Y,Nakashima O,Matsuyama Y.Comparison of resection and ablation for hepatocellular carcionoma: a cohort study based on a Japanese nationwide survey.J Hepatol2013;58:724-9

[19]

Huang J,Cheng Z,Du L,Xu Y.A randomized trial comparing radiofrequency ablation and surgical resection for HCC conforming to the Milan criteria.Ann Surg2010;252:903-12

[20]

Pawlik TM,Abdalla EK,Nagormey DM,Kianmanesh R,Curley SA,Lauwers GY.Hepatectomy for hepatocellular carcinoma with major portal or hepatic vein invasion: results of a multicenter study.Surgery2005;137:403-10

[21]

Kokudo T,Matsuyama Y,Izumi N,Kudo M,Sakamoto M,Kaneko S.Survival benefit of liver resection for hepatocellular carcinoma associated with portal vein invasion.J Hepatol2016;65:938-943

[22]

Luo J,Lai EC,Lau WY,Shi M.Transarterial chemoembolization for unresectable hepatocellular carcinoma with portal vein tumor thrombosis: a prospective comparative study.Ann Surg Oncol2011;18:413-20

[23]

Bruix J,Sherman M,Bolondi L,Galle PR,Beaugrand M,Porta C,Marrero JA,Shan M,Voliotis D.Efficacy and safety of sorafenib in patients with advanced hepatocellular carcinoma: subanalyses of a phase III trial.J Hepatol2012;57:821-9

[24]

Nouso K,Uchida D,Izumi N,Ichida T,Ku Y,Sakamoto M,Takayama T,Matsuyama Y.Effect of hepatic arterial infusion chemotherapy of 5-fluorouracil and cisplatin for advanced hepatocellular carcinoma in the Nationwide Survey of Primary Liver Cancer in Japan.Br J Cancer2013;109:1904-7 PMCID:PMC3790188

[25]

Heimbach JK,Finn RS,Abecassis MM,Zhu AX,Marrero JA.AASLD guidelines for the treatment of hepatocellular carcinoma.Hepatology2018;67:358-80

[26]

Qin S.Guidelines on the diagnosis and treatment of primary liver cancer (2011 edition).Chin Clin Oncol2012;1:10

[27]

Zhou Y,Wu L.Meta-analysis of anatomic resection versus nonanatomic resection for hepatocellular carcinoma.Langenbecks Arch Surg2011;396:1109-17

[28]

Cucchetti A,Ercolani G,Torzilli G.A comprehensive meta-regression analysis on outcome of anatomic resection versus nonanatomic resection for hepatocellular carcinoma.Ann Surg Oncol2012;19:3697-705

[29]

Eguchi S,Arii S,Okita K,Ikai I,Kojiro M,Monden M,Nakamura Y.Comparison of outcomes between an anatomical subsegmentectomy and a non-anatomical minor hepatectomy for single hepatocellular carcinomas based on a Japanese nationwide survey.Surgery2008;143:469-75

[30]

Shindoh J,Matsuyama Y,Arita J,Hasegawa K.Complete removal of the tumor-bearing portal territory decreases local tumor recurrence and improves disease-specific survival of patients with hepatocellular carcinoma.J Hepatol2016;64:594-600

[31]

Lim C,Miyata A,Sakamoto Y,Sugawara Y.Surgical indications and procedures for resection of hepatic malignancies confined to segment VII.Ann Surg2016;263:529-37

[32]

Cucchetti A,Cescon M,Xia Y,Shen F.Anatomic versus nonanatomic resection in cirrhotic patients.Surgery2014;155:512-21

[33]

Marubashi S,Akita H,Ito Y,Ishikawa O.Anatomical versus non-anatomical resection for hepatocellular carcinoma.Br J Surg2015;102:776-84

[34]

Hirokawa F,Nagano H,Kaibori M,Takemura S,Nakata Y,Ishizaki M.Do patients with small solitary hepatocellular carcinomas without macroscopically vascular invasion require anatomic resection? Propensity score analysis.Surgery2015;157:27-36

[35]

Makuuchi M,Yamazaki S.Four new hepatectomy procedures for resection of the right hepatic vein and preservation of the inferior right hepatic vein.Surg Gynecol Obstet1987;164:68-72

[36]

Makuuchi M,Yamazaki S.Ultrasonically guided subsegmentectomy.Surg Gynecol Obstet1985;161:346-50

[37]

Takasaki K,Tanaka S,Yamamoto M.Highly anatomically systematized hepatic resection with Glissonean sheath code transection at the hepatic hilus.Int Surg1990;75:73-7

[38]

Yamamoto M,Ariizumi S,Takahashi Y.Glissonean pedicle transection method for liver surgery (with video).J Hepatobiliary Pancreat Sci2012;19:3-8 PMCID:PMC3233661

[39]

Kawasaki S,HaradaH,Kosuge T.A new alternative hepatectomy method for resection of segments 3 and 4 of the liver.Surg Gynecol Obstet1992;175:267-9

[40]

Midorikawa Y.Caudate lobectomy (segmentectomy 1) (with video).J Hepatobiliary Pancreat Sci2012;19:48-53

[41]

Takayama T,Higaki T,Teshima Y.High dorsal resection of the liver.J Am Coll Surg1994;179:72-5

[42]

Yamamoto J,Shimada K,Takayama T.Anterior transhepatic approach for isolated resection of the caudate lobe of the liver.World J Surg1999;23:97-101

[43]

Yin Z,Ye H,Wang J.Short- and long-term outcomes after laparoscopic and open hepatectomy for hepatocellular carcinoma: a global systematic review and meta-analysis.Ann Surg Oncol2013;20:1203-15

[44]

Xiong JJ,Javed MA,Mukherjee R,Sutton R,Hu WM.Meta-analysis of laparoscopic vs open liver resection for hepatocellular carcinoma.World J Gastroenterol2012;18:6657-68 PMCID:PMC3516221

[45]

Takahara T,Beppu T,Hasegawa K,Hatano E,Mizuguchi T,Ikeda T,Taniai N,Tanabe M,Konishi M,Sugioka A,Taketomi A,Kubo S,Miyata H,Kaneko H,Miyazaki M.Long-term and perioperative outcomes of laparoscopic versus open liver resection for hepatocellular carcinoma with propensity score matching: a multi-institutional Japanese study.J Hepatobiliary Pancreat Sci2015;22:721-7

[46]

MoriseZ,Cherqui D,Belli G.Can we expand the indications for laparoscopic liver resection? A systematic review and meta-analysis of laparoscopic liver resection for patients with hepatocellular carcinoma and chronic liver disease.J Hepatobiliary Pancreat Sci2015;22:342-52

[47]

Twaji A,Sodergren MH,Darzi A.Laparoscopic vs open approach to resection of hepatocellular carcinoma in patients with known cirrhosis: systematic review and meta-analysis.World J Gastroenterol2014;20:8274-81 PMCID:PMC4081703

[48]

Kanazawa A,Shimizu S,Yamazoe S,Kubo S.Impact of laparoscopic liver resection for hepatocellular carcinoma with F4-liver cirrhosis.Surg Endosc2013;27:2592-7

[49]

Wakabayashi G,Geller DA,Kaneko H,Asbun H,Tanabe M,Tsung A,Machado MA,Troisi RI,Van Dam,Abu Hilal,Kwon CH,Choi GH,Cai X,Chen KH,Sugioka A,Herman P,Chen XP,Jarnagin W,Strong R,Lo CM,Kokudo N,Strasberg SM.Recommendations for laparoscopic liver resection: a report from the second international consensus conference held in Morioka..Ann Surg2015;261:619-29

[50]

Tang YH,Chen X.Resection margin in hepatectomy for hepatocellular carcinoma: a systematic review.Hepatogastroenterology2012;59:1393-7

[51]

Poon RT,Ng IO.Significance of resection margin in hepatectomy for hepatocellular carcinoma: a critical reappraisal.Ann Surg2000;231:544-51 PMCID:PMC1421031

[52]

Arii S,Yamazoe Y,Morino T,Maetani S.Predictive factors for intrahepatic recurrence of hepatocellular carcinoma after partial hepatectomy.Cancer1992;69:913-9

[53]

Kawasaki S,Miyagawa S,Hayashi K,Miwa S,Nishimaki K.Results of hepatic resection for hepatocellular carcinoma.World J Surg1995;19:31-4

[54]

Kosuge T,Takayama T,Shimada K.Long-term results after resection of hepatocellular carcinoma: experience of 480 cases.Hepatogastroenterology1993;40:328-32

[55]

Hu W,Guo W,Zhang B.Relationship of different surgical margins with recurrence-free survival in patients with hepatocellular carcinoma.Int J Clin Exp Pathol2015;8:3404-9 PMCID:PMC4440187

[56]

Shi M,Lin XJ,Chen MS,Lau WY.Partial hepatectomy with wide versus narrow resection margin for solitary hepatocellular carcinoma: a prospective randomized trial.Ann Surg2007;245:36-43 PMCID:PMC1867934

[57]

Poon RT,Fan ST,Lo CM,Wong J.Clinicopathologic features of long-term survivors and disease-free survivors after resection of hepatocellular carcinoma: a study of a prospective cohort.J Clin Oncol2001;19:3037-44

[58]

Imamura H,Tanaka E,Hasegawa K,Sugawara Y,Takayama T,Makuuchi M.Risk factors contributing to early and late phase intrahepatic recurrence of hepatocellular carcinoma after hepatectomy.J Hepatol2003;38:200-7

[59]

Yang LY,Ou DP,Zeng ZJ.Solitary large hepatocellular carcinoma: a specific subtype of hepatocellular carcinoma with good outcome after hepatic resection.Ann Surg2009;249:118-23

[60]

Franco D,Smadja C,Meakins J,Grange D.Resection of hepatocellular carcinomas.Results in 72 European patients with cirrhosis. Gastroenterology1990;98:733-8

[61]

Ishizuka M,Kita J,Kato M.Impact of an inflammation-based prognostic system on patients undergoing surgery for hepatocellular carcinoma: a retrospective study of 398 Japanese patients.Am J Surg2012;203:101-6

[62]

Mano Y,Yamashita Y,Tsujita E,Aishima S,Yoshizumi T,Maehara Y.Preoperative neutrophil-to-lymphocyte ratio is a predictor of survival after hepatectomy for hepatocellular carcinoma: a retrospective analysis.Ann Surg2013;258:301-5

[63]

Voron T,Pietrasz D,Laurent A,Salloum C,Azoulay D.Sarcopenia impacts on short- and long-term results of hepatectomy for hepatocellular carcinoma.Ann Surg2015;261:1173-83

[64]

Utsunomiya T,Kudo M,Izumi N,Sakamoto M,Ku Y,Kokudo N.A comparison of the surgical outcomes among patients with HBV-positive, HCV-positive, and non-B non-C hepatocellular carcinoma: a nationwide study of 11950 patients.Ann Surg2015;261:513-20

[65]

Garancini M,Romano F,Degrate L,Gianotti L.Surgical management of hepatocellular carcinoma within and beyond BCLC indications in a middle volume center.J Visc Surg2018;17:S1878-86

[66]

Wu F,Wu J,Tian F.Analysis of risk factors of recurrence in patients with BCLC 0-A hepatocellular carcinoma after surgical resection.Zhonghua Yi Xue Za Zhi2015;95:1747-50

[67]

Jiang L,Wen T,Zeng Y,Wang W,Wu H.Comparison of outcomes of hepatic resection and radiofrequency ablation for hepatocellular carcinoma patients with multifocal tumors meeting the Barcelona-Clinic Liver Cancer stage A classification.J Am Coll Surg2015;221:951-61

[68]

Li J,Liu CF,Yan JJ,Wu MC.Risk factors and surgical outcomes for spontaneous rupture of BCLC stages A and B hepatocellular carcinoma: a case-control study.World J Gastoenterol2014;20:9121-7 PMCID:PMC4112877

[69]

Xu W,Xu G,Hu D,Yang H,Lu X.Management of intrahepatic recurrence after resection for hepatocellular carcinoma exceeding the barcelona clinic liver cancer criteria.Oncotarget2017;8:110406-14 PMCID:PMC5746392

[70]

Wang K,Hidaka M,Soyama A,Huang M,Zou S.Comparison of the outcomes of hepatocellular carcinoma after hepatectomy between two regional medical centers in China and Japan.Asian J Surg2017;40:380-8

[71]

Shrager B,Tabrizian P,Labow DM.Resection of large hepatocellular carcinoma (≥10 cm): a unique western perspective.J Surg Oncol2013;107:111-7

[72]

Lee SG,Jung JP,Kim KH.Outcome of patients with huge hepatocellular carcinoma after primary resection and treatment of recurrent lesions.Br J Surg2007;94:320-6

[73]

Shah SA,Cleary SP,Gilvray ID,Grant DR.Prognosis and results after resection of very large (>or=10 cm) hepatocellular carcinoma.J Gastrointest Surg2007;11:589-95

[74]

Pandey D,Wai CT,Tan KC.Long term outcome and prognostic factors for large hepatocellular carcinoma (10 cm or more) after surgical resection.Ann Surg Oncol2007;14:2817-23

[75]

Ng KK,Pawlik TM,Regimbeau JM,Ikai I,Curley SA,Ng IO,Poon RT.Is hepatic resection for large or multinodular hepatocellular carcinoma justified? Results from a multi-institutional database.Ann Surg Oncol2005;12:364-73

[76]

Roayaie S,Taouli B.Resection of hepatocellular carcinoma with macroscopic vascular invasion.Ann Surg Oncol2013;20:3754-60

[77]

Ban D,Yamamoto Y,Esaki M,Kosuge T.Efficacy of a hepatectomy and a tumor thrombectomy for hepatocellular carcinoma with tumor thrombus extending to the main portal vein.J Gastrointest Surg2009;13:1921-8

[78]

Vitale A,Boccagni P,D'Amico F,Neri D,Valmasoni M,Carraro A,Pauletto A,Polacco M,Farinati F,Romano A,Cillo U.Validation of the BCLC prognostic system in surgical hepatocellular cancer patients.Transplant Proc2009;41:1260-3

PDF

52

Accesses

0

Citation

Detail

Sections
Recommended

/