Elimination of hepatitis from Pakistan by 2030: is it possible?

Yasir Waheed , Masood Siddiq

Hepatoma Research ›› 2018, Vol. 4 : 45

PDF
Hepatoma Research ›› 2018, Vol. 4:45 DOI: 10.20517/2394-5079.2018.58
Opinion
Opinion

Elimination of hepatitis from Pakistan by 2030: is it possible?

Author information +
History +
PDF

Abstract

Globally 71 million people are living with hepatitis C virus (HCV) out which 7.1 million (10%) are present in Pakistan. Genotype 3 is the most common HCV type in the country. World Health Organization is working with health authorities in different countries for effective control of HCV, to reduce its incidence by 90% and to reduce hepatitis related mortality by 65% by the year 2030. There are several challenges that hinder elimination of HCV from Pakistan including the lack of patient awareness about the causes and transmission of disease, lack of affordability for investigations and drug treatment and lack of experienced healthcare professionals. Other major contributors to achieve HCV elimination are lack of effective drugs and delayed regulatory approvals combined with compromised monitoring by health authorities and lack of robust epidemiological data. Efforts are needed to educate the public about the modes of transmission and prevention of HCV infection, and massively upscale screening along with treatment. There is a dire need to prevent more than 200,000 new infections that occur each year in Pakistan. Given the scale of the problem, it is very unlikely that the government alone can handle it.

Keywords

Hepatitis C virus / global health sector strategy / hepatitis elimination / national hepatitis strategic framework / punjab hepatitis ordinance / hepatitis diagnosis / screening

Cite this article

Download citation ▾
Yasir Waheed, Masood Siddiq. Elimination of hepatitis from Pakistan by 2030: is it possible?. Hepatoma Research, 2018, 4: 45 DOI:10.20517/2394-5079.2018.58

登录浏览全文

4963

注册一个新账户 忘记密码

References

[1]

GBD 2013 mortality and causes of death collaborators..Global, regional and national age-sex specific all cause and cause specific mortality for 240 causes of death, 1990-2013: a systematic analysis for the global burden of diseases study 2013.Lancet2015;385:117-71

[2]

Waheed Y.Transition from millennium development goals to sustainable development goals and hepatitis.Pathog Glob Health2015;109:353 PMCID:PMC4809236

[3]

World Health Organization. Global Health Sector Strategies on Viral Hepatitis 2016-2021. Published 22 April 2016. Available from: http://apps.who.int/gb/ebwha/pdf_files/WHA69/A69_32-en.pdf?ua=1. [Last accessed on 9 Aug 2018].

[4]

Polaris Observatory HCV collaborators..Global prevalence and genotype distribution of hepatitis C infection in 2015: a modelling study.Lancet Gastroenterol Hepatol2017;2:161-76

[5]

World Health Organization. Progress report on access to hepatitis C treatment, focus on overcoming barriers in low and middle income countries. Published March 2018. Available from: http://apps.who.int/iris/bitstream/10665/260445/1/WHO-CDS-HIV-18.4-eng.pdf?ua=1. [Last accessed on 9 Aug 2018].

[6]

Polaris Observatory. Center for Disease Analysis. Available from: http://cdafound.org/polaris/. [Last accessed on 9 Aug 2018].

[7]

National Hepatitis Strategic Framework for Pakistan (2017-2021). Available from: http://phrc.org.pk/Extra/NHSF.pdf. [Last accessed on 9 Aug 2018]

[8]

Waheed Y,Safi,Qadri I.Hepatitis C virus in Pakistan: a systematic review of prevalence, genotypes and risk factors.World J Gastroenterology2009;15:5647-53 PMCID:PMC2789216

[9]

Aziz H,Murtaza S,Waheed Y.Predictors of response to antiviral therapy in patients with chronic hepatitis C from Pakistani population.Chin Med J2011;124:1333-7

[10]

Aziz H,Waheed Y,Raza A,Athar MA.Evaluation of prognostic factors for peg interferon alfa-2b plus ribavirin treatment on HCV infected patients in Pakistan.Infect Genet Evol2011;11:640-5

[11]

Aziz H,Waheed Y,Gil ML.Analysis of variables and interactions among variables associated with a sustained virological response to pegylated interferon alpha 2a plus ribavirin in hepatitis C virus genotype 3 infected patients.Int J Infect Dis2012;16:e597-602

[12]

Jamil Z,Malik M.Effect of sofosuvir plus ribavirin therapy on hepatitis C patients in Pakistan: a retrospective study.Peer J2018;6:e4853 PMCID:PMC5971832

[13]

Lim AG,Mahmood H,Davies CF,Glass N,Fraser H,Mukandavire C,Martin NK,Averhoff F.Curbing the hepatitis C virus epidemic in Pakistan: the impact of scaling up treatment and prevention for achieving elimination.Int J Epidemiology2018;

[14]

Qureshi H,Jooma R,Afridi HUR.Prevalence of hepatitis B and C viral infections in Pakistan: findings of a national survey appealing for efeective prevention and control measures.East Mediterr Health J2010;16:S15-23

[15]

Saeed U,Ashraf M,Anjum S.Estimation of hepatitis B virus, hepatitis C virus, and different clinical parameters in the thalaseemic population of capital twin cities of Pakistan.Virology (Auckl).2015;6:11-6 PMCID:PMC4636113

[16]

Waheed Y,Aziz H,Imran M.Prevalence of hepatitis C in people who inject drugs in the cities of Rawalpindi and Islamabad, Pakistan.Biomed Rep2017;7:263-6 PMCID:PMC5582579

[17]

Omran H. World Bank to lend Health Ministry $200m for hepatitis C screening: minister. Available from: https://dailynewsegypt.com/2018/03/28/world-bank-lend-health-ministry-200m-hepatitis-c-screening-minister/. [Last accessed on 9 Aug 2018].

[18]

Papatheodoridis GV,Cholongitas E,Baskozos I,Colombo M,Craxi A,Gore C,Lazarus JV,Peck-Radosavljevic M,Schatz E,van Damme P,Yazdanpanah Y,Manns MP.Hepatitis C: the beginning of the end-key elements for successful European and national strategies to eliminate HCV in Europe.J Viral Hepatitis2018;Suppl 1:6-17

[19]

Waheed Y.Hepatitis C eradication: a long way to go.World J Gastroenterol2015;21:12510-2 PMCID:PMC4649134

PDF

224

Accesses

0

Citation

Detail

Sections
Recommended

/