Hepatocellular carcinoma and type 2 diabetes mellitus: cytokeratin 8/18 expression in hepatocellular carcinoma and glycogen-storing hepatocytes

Kunio Takegoshi , Eikichi Okada , Qin Su

Hepatoma Research ›› 2016, Vol. 2 : 229 -30.

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Hepatoma Research ›› 2016, Vol. 2:229 -30. DOI: 10.20517/2394-5079.2016.26
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Hepatocellular carcinoma and type 2 diabetes mellitus: cytokeratin 8/18 expression in hepatocellular carcinoma and glycogen-storing hepatocytes

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Kunio Takegoshi, Eikichi Okada, Qin Su. Hepatocellular carcinoma and type 2 diabetes mellitus: cytokeratin 8/18 expression in hepatocellular carcinoma and glycogen-storing hepatocytes. Hepatoma Research, 2016, 2: 229-30 DOI:10.20517/2394-5079.2016.26

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References

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Takegoshi K,Nomoto K,Sawasaki T,Terakawa H,Yabushita K,Terahata S.Hepatocellular carcinoma and type 2 diabetes mellitus: two cases highlighting changes in tumor glycogen content..Hepatoma Res2016;2:26-30

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Bannasch P,Mayer D.Early bioenergetic changes in hepatocarcinogenesis: preneoplastic phenotypes mimic responses to insulin and thyroid hormone..J Bioenerg Biomembr1997;29:303-13

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Strnad P,Jang KH.Keratins: markers and modulators of liver disease..Curr Opin Gastroenterol2012;28:209-16

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Su Q,Otto G.Cytokeratin expression is reduced in glycogenotic clear hepatocytes but increased in ground-glass cells in chronic human and woodchuck hepadnaviral infection..Hepatology1998;28:347-59

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Mathew J,Gilbert S,Marceau N.Keratin 8/18 regulation of glucose metabolism in normal versus cancerous hepatic cells through differential modulation of hexokinase status and insulin signaling..Exp Cell Res2013;319:474-86

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