Mesenchymal Stem Cells in Clinical Trials for Immune Disorders

Zongjin Li, Zhibo Han, Zhong-Chao Han

Global Medical Genetics ›› 2024, Vol. 11 ›› Issue (03) : 196-199.

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Global Medical Genetics ›› 2024, Vol. 11 ›› Issue (03) : 196-199. DOI: 10.1055/s-0044-1788044
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Mesenchymal Stem Cells in Clinical Trials for Immune Disorders

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Zongjin Li, Zhibo Han, Zhong-Chao Han. Mesenchymal Stem Cells in Clinical Trials for Immune Disorders. Global Medical Genetics, 2024, 11(03): 196‒199 https://doi.org/10.1055/s-0044-1788044

References

[1]
Li Z, Han ZC. Introduction of perinatal tissue-derived stem cells. In: Han ZC, Takahashi TA, Li Z. eds. Perinatal Stem Cells: Biology, Manufacturing and Translational Medicine. Singapore; Springer Singapore; 2019: 1-7
[2]
Ji YR, Yang ZX, Han Z-B, et al. Mesenchymal stem cells support proliferation and terminal differentiation of B cells. Cell Physiol Biochem 2012; 30(06) 1526-1537
[3]
Zhao Q, Han Z, Wang J, Han Z. Development and investigational new drug application of mesenchymal stem/stromal cells products in China. Stem Cells Transl Med 2021; 10(Suppl. 02) S18-S30
[4]
Hezam K, Fu E, Zhang J, Li Z. Therapeutic trends of priming mesenchymal stem cells: a bibliometric analysis. Biochem Biophys Rep 2024; 38: 101708
[5]
Shi Y, Wang Y, Li Q, et al. Immunoregulatory mechanisms of mesenchymal stem and stromal cells in inflammatory diseases. Nat Rev Nephrol 2018; 14(08) 493-507
[6]
Chen Y, Xu Y, Chi Y, et al. Efficacy and safety of human umbilical cord-derived mesenchymal stem cells in the treatment of refractory immune thrombocytopenia: a prospective, single arm, phase I trial. Signal Transduct Target Ther 2024; 9(01) 102
[7]
Chen H. Stem cell translational medicine: the Tianjin model revisited. Stem Cells Transl Med 2021; 10(Suppl. 02) S4-S9
[8]
Fang L, Meikuang L, Ye G, et al. Successful treatment of a 19-month-old boy with hepatitis associated aplastic anemia by infusion of umbilical cord-derived mesenchymal stromal cells: a case report. Cell Transplant 2021; 30: 963689720977144
[9]
Han ZC, Takahashi TA, Han Z, Li Z. Perinatal Stem Cells. Singapore:: Springer; 2019
[10]
Liang W, Chen X, Zhang S, et al. Mesenchymal stem cells as a double-edged sword in tumor growth: focusing on MSC-derived cytokines. Cell Mol Biol Lett 2021; 26(01) 3
[11]
Du WJ, Chi Y, Yang ZX, et al. Heterogeneity of proangiogenic features in mesenchymal stem cells derived from bone marrow, adipose tissue, umbilical cord, and placenta. Stem Cell Res Ther 2016; 7(01) 163
[12]
Huang Y, Wu Q, Tam PKH. Immunomodulatory mechanisms of mesenchymal stem cells and their potential clinical applications. Int J Mol Sci 2022; 23(17) 10023
[13]
Cao X, Duan L, Hou H, et al. IGF-1C hydrogel improves the therapeutic effects of MSCs on colitis in mice through PGE2-mediated M2 macrophage polarization. Theranostics 2020; 10(17) 7697-7709
[14]
Huang A, Liu Y, Qi X, et al. Intravenously transplanted mesenchymal stromal cells: a new endocrine reservoir for cardioprotection. Stem Cell Res Ther 2022; 13(01) 253
[15]
Wysoczynski M, Khan A, Bolli R. New paradigms in cell therapy: repeated dosing, intravenous delivery, immunomodulatory actions, and new cell types. Circ Res 2018; 123(02) 138-158
[16]
Leibacher J, Henschler R. Biodistribution, migration and homing of systemically applied mesenchymal stem/stromal cells. Stem Cell Res Ther 2016; 7: 7

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