Chemical composition and antimicrobial activity of the essential oil of (Maxim.) Hand.-Mazz

Abstract

Essential oil of the subterranean part of Cacalia tangutica (Maxim.) Hand.-Mazz was analyzed by gas chromatography (GC)-mass spectrum (MS) technique in two different capillary columns of different polarities. Thirty-one components were identified in the oil and the main compounds were ?-zingiberene (13.49%), germacrene D (10.76%), ?-pinene (8.54%), caryophyllene(Z-) (6.36%), linalool (6.16%), ?-myrcene (4.89%), ?-ocimene(Z-) (4.40%)and ocimenone(Z-) (3.58%). The antimicrobial activity of the oil was evaluated against 2 fungi and 12 bacteria including 6 clinically isolated strains using the agar disc diffusion and broth microdilution methods. The results show that the oil presented a broad antimicrobial spectrum and had better antimicrobial activity against yeast and gram-positive bacteria. The minimum inhibitory concentration values were 0.16–5.00 g/L and minimum bactericidal concentration values were 0.16–5.00 g/L.

Keywords

Cacalia tangutica / antimicrobial activity / essential oil / gas chromatography (GC)-mass spectrum (MS)