An integrated pipeline model for biomedical entity alignment

Yu HU, Tiezheng NIE, Derong SHEN, Yue KOU, Ge YU

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PDF(496 KB)
Front. Comput. Sci. ›› 2021, Vol. 15 ›› Issue (3) : 153321. DOI: 10.1007/s11704-020-8426-4
RESEARCH ARTICLE

An integrated pipeline model for biomedical entity alignment

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Abstract

Biomedical entity alignment, composed of two subtasks: entity identification and entity-concept mapping, is of great research value in biomedical text mining while these techniques are widely used for name entity standardization, information retrieval, knowledge acquisition and ontology construction.

Previous works made many efforts on feature engineering to employ feature-basedmodels for entity identification and alignment. However, the models depended on subjective feature selection may suffer error propagation and are not able to utilize the hidden information.With rapid development in healthrelated research, researchers need an effective method to explore the large amount of available biomedical literatures.

Therefore, we propose a two-stage entity alignment process, biomedical entity exploring model, to identify biomedical entities and align them to the knowledge base interactively. The model aims to automatically obtain semantic information for extracting biomedical entities and mining semantic relations through the standard biomedical knowledge base. The experiments show that the proposed method achieves better performance on entity alignment. The proposed model dramatically improves the F1 scores of the task by about 4.5% in entity identification and 2.5% in entity-concept mapping.

Keywords

entity alignment / biomedical text mining / neural network model

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Yu HU, Tiezheng NIE, Derong SHEN, Yue KOU, Ge YU. An integrated pipeline model for biomedical entity alignment. Front. Comput. Sci., 2021, 15(3): 153321 https://doi.org/10.1007/s11704-020-8426-4

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