Frontiers of Agriculture in China >
Regulation of the type IIb sodium-dependent phosphate cotransporter expression in the intestine
Received date: 26 Jul 2008
Accepted date: 29 Oct 2008
Published date: 05 Jun 2009
Copyright
Phosphate (Pi) plays important roles in growth, development, bone mineralization, energy metabolism, nucleic acid synthesis, cell signaling, and acid–base regulation. The rate of intestinal absorption of Pi is a major determinant of Pi homeostasis. The type IIb sodium-dependent Pi cotransporter (NaPi-IIb) is responsible for intestinal Pi absorption. Many physiological factors regulate the rate of Pi absorption via modulating the expression of NaPi-IIb in the intestine. In this review, we summarize the role of these factors in the regulation of NaPi-IIb expression in the intestine.
Key words： NaPi-IIb; expression; intestine; regulation
Bin WANG , Yulong YIN . Regulation of the type IIb sodium-dependent phosphate cotransporter expression in the intestine[J]. Frontiers of Agriculture in China, 2009 , 3(2) : 226 -230 . DOI: 10.1007/s11703-009-0037-7
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