REVIEW

Regulation of the type IIb sodium-dependent phosphate cotransporter expression in the intestine

  • Bin WANG , 1 ,
  • Yulong YIN , 2
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  • 1. Department of Food Engineering, Jiangsu Food Science College, Huai’an 223003, China
  • 2. Laboratory of Animal Nutrition and Health and Key Laboratory of Agro-Ecology, Institute of Subtropical Agriculture, The Chinese Academy of Sciences, Changsha, Hunan 410125, China

Received date: 26 Jul 2008

Accepted date: 29 Oct 2008

Published date: 05 Jun 2009

Copyright

2014 Higher Education Press and Springer-Verlag Berlin Heidelberg

Abstract

Phosphate (Pi) plays important roles in growth, development, bone mineralization, energy metabolism, nucleic acid synthesis, cell signaling, and acid–base regulation. The rate of intestinal absorption of Pi is a major determinant of Pi homeostasis. The type IIb sodium-dependent Pi cotransporter (NaPi-IIb) is responsible for intestinal Pi absorption. Many physiological factors regulate the rate of Pi absorption via modulating the expression of NaPi-IIb in the intestine. In this review, we summarize the role of these factors in the regulation of NaPi-IIb expression in the intestine.

Cite this article

Bin WANG , Yulong YIN . Regulation of the type IIb sodium-dependent phosphate cotransporter expression in the intestine[J]. Frontiers of Agriculture in China, 2009 , 3(2) : 226 -230 . DOI: 10.1007/s11703-009-0037-7

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