Exploration Editors’ Favorite Research in 2025

Exploration ›› 2026, Vol. 6 ›› Issue (1) :70143 DOI: 10.1002/exp2.70143

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. Exploration Editors’ Favorite Research in 2025. Exploration, 2026, 6 (1) : 70143 DOI:10.1002/exp2.70143

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[1]	J. Koppe, A. V. Yakimov, D. Gioffre, et al., “Coordination Environments of Pt Single-Atom Catalysts From NMR Signatures,” Nature 642 (2025): 613–619, https://doi.org/10.1038/s41586-025-09068-x.

[2]	S. Fu, J. Li, J. Chen, et al., “Bacteriophage λ Exonuclease and a 5′-Phosphorylated DNA Guide Allow PAM-Independent Targeting of Double-Stranded Nucleic Acids,” Nature Biotechnology 43 (2025): 1144–1155, https://doi.org/10.1038/s41587-024-02388-9.

[3]	Y. Chen, J. Sun, K. Shi, et al., “Glycolysis-Compatible Urethanases for Polyurethane Recycling,” Science 390 (2025): 503–509, https://doi.org/10.1126/science.adw4487.

[4]	M. Pittaluga, Y. S. Lo, A. Brzosko, et al., “Long-Distance Coherent Quantum Communications in Deployed Telecom Networks,” Nature 640 (2025): 911–917, https://doi.org/10.1038/s41586-025-08801-w.

[5]	X. Bao, F. Wang, J. Zhang, et al., “Real-Time In Situ Magnetization Reprogramming for Soft Robotics,” Nature 645 (2025): 375–384, https://doi.org/10.1038/s41586-025-09459-0.

[6]	B. Zheng, Z. Lu, S. Wang, et al., “Computational Design of Superstable Proteins Through Maximized Hydrogen Bonding,” Nature Chemistry 18 (2025): 364–373, https://doi.org/10.1038/s41557-025-01998-3.

[7]	R. Xie, F. Han, Q. Yu, et al., “A Movable Long-Term Implantable Soft Microfibre for Dynamic Bioelectronics,” Nature 645 (2025): 648–655, https://doi.org/10.1038/s41586-025-09344-w.

[8]	X. Huang, C. Liu, S. N. Sharma, et al., “Oral Delivery of Liquid mRNA Therapeutics by an Engineered Capsule for Treatment of Preclinical Intestinal Disease,” Science Translational Medicine 17 (2025): eadu1493, https://doi.org/10.1126/scitranslmed.adu1493.

[9]	S. L. Piper, L. Melag, M. Kar, et al., “Organic Ionic Plastic Crystals Having Colossal Barocaloric Effects for Sustainable Refrigeration,” Science 387 (2025): 56–62, https://doi.org/10.1126/science.adq8396.

[10]	M. Li, Z. Jiang, X. Xu, et al., “Chromatin Accessibility Landscape of Mouse Early Embryos Revealed by Single-Cell NanoATAC-Seq2,” Science 387 (2025): eadp4319, https://doi.org/10.1126/science.adp4319.