The therapeutic potential of interleukin-2/anti-interleukin-2 antibody complex in cold storage-associated kidney transplantation

Keywords

IL-2/anti-IL-2 antibody complex / kidney transplantation / regulatory T cells

References

[1] BhandariSK, ZhouH, ShawSF, et al. Causes of death in end-stage kidney disease: comparison between the United States renal data system and a large integrated health care system. Am J Nephrol. 2022;53(1):32-40.

[2] KandaswamyR, StockPG, MillerJM, et al. OPTN/SRTR 2022 Annual Data Report: pancreas. Am J Transplant. 2024;24(2s1):S119-s175.

[3] LerinkLJSDE, KokMJC, MulveyJF, et al. Preclinical models versus clinical renal ischemia reperfusion injury: a systematic review based on metabolic signatures. Am J Transplant. 2022;22(2):344-370.

[4] HelanteräI, Ibrahim HN, LempinenM, et al. Donor age, cold ischemia time, and delayed graft function. Clin J Am Soc Nephrol. 2020;15(6):813-821.

[5] ZhuJ, ZhangG, SongZ, et al. Protein kinase C-delta mediates kidney tubular injury in cold storage-associated kidney transplantation. J Am Soc Nephrol. 2020;31(5):1050-1065.

[6] ZhuJ, XiangX, HuX, et al. miR-147 represses NDUFA4, inducing mitochondrial dysfunction and tubular damage in cold storage kidney transplantation. J Am Soc Nephrol. 2023;34(8):1381-1397.

[7] HuM, RogersNM, LiJ, et al. Antigen specific regulatory T cells in kidney transplantation and other tolerance settings. Front Immunol. 2021;12:717594.

[8] Martin-MorenoPL, Tripathi S, ChandrakerA. Regulatory T cells and kidney transplantation. Clin J Am Soc Nephrol. 2018;13(11):1760-1764.

[9] WangYM, Alexander SI. IL-2/anti-IL-2 complex: a novel strategy of in vivo regulatory T cell expansion in renal injury. J Am Soc Nephrol. 2013;24(10):1503-1504.

[10] JangJY, KimHW, YanJJ, et al. Interleukin-2/anti-interleukin-2 immune complex attenuates cold ischemia-reperfusion injury after kidney transplantation by increasing renal regulatory T cells. Clin Transl Med. 2024;14(3):e1631.

RIGHTS & PERMISSIONS

2024 2024 The Author(s). Clinical and Translational Discovery published by John Wiley & Sons Australia, Ltd on behalf of Shanghai Institute of Clinical Bioinformatics.