Enzymes in Nanomedicine for Anti-tumor Therapy

Abstract

Natural enzymes are biological macromolecules catalyzing reactions in living organisms and regulating biological processes. Targeted delivery of enzymes into tumor tissues for anti-tumor therapy through nanotechnology has attracted emerging interest in recent years. In this paper, we systematically summarize the latest research progress on enzymes that used for anti-tumor therapy in nanomedicine with different action mechanisms, including anti-tumor principles, delivery modes, response modes, and synergistic therapeutic design of these enzymes. Finally, we discuss the challenges and future prospects of enzymes for anti-tumor nanomedicine.

Keywords

Enzyme / Nanomedicine / Protein delivery / Cancer therapy

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