A Chemical Approach for Real-time Monitoring Neuronal Activities

Abstract

In the latest issue of Nature Nanotechnology, Ling and coworkers reported the first potassium nanosensor applicable in a freely moving animal. It was developed by embedding the mesoporous silica nanoparticle framework with optical potassium indicators and then shielding the framework with an ultrathin layer of a potassium-permeable membrane. This nanosensor achieved highly sensitive monitoring of the dynamic changes of the extracellular potassium in the brain of freely moving mice with epilepsy.

References

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