Electrochemistry Enabling Stereoselective Diamination of Alkenes

Abstract

To achieve the stereoselective and regioselective diamination of alkenes, Xu et al. developed an electro-chemical protocol for the diamination of aryl alkenes with sulfamides by using triarylamine as a redox mediator. The chemistry proceeded in an undivided cell under constant current conditions, featuring not only wide scope of substrates and reasonable yields, but also excellent diastereoselectivity(>20:1 dr) and regioselectivity. This work has been published in the Nature Communications and can be reached at https://doi.org/10.1038/s41467-019-13024-5.

References

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[4] Cai C. Y., Shu X. M., Xu H. C., Nature Communications, 2019, https://doi.org/10.1038/s41467-019-13024-5