Tandem Approach to Functionalized Pyrrolo[3,4-a]carbazole-1,3-diones via a Pd-catalyzed Indole-to-carbazole Transformation

Abstract

A one-pot and efficient three-component reaction of indoles, acrylates and maleimides for the synthesis of pyrrolo[3,4-a]carbazole-1,3-dione derivatives was developed. Theree C-C bonds and one ring were created in a single step via an indole-to-carbazole transformation triggered by Pd(II)-catalyzed direct C3-alkenylation of indoles.

Keywords

Carbazole / One-pot / Tandem reaction / Three-component reaction / Indole-to-carbazole

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