Synthesis and biological evaluation of novel saccharin derivatives containing 1,2,3-triazole moiety

Xiaobin Tang; Zhenghui Li; Yonghong Li; Wei Liu; Peng Yu; Lixin Li; Yu Guo; Cheng Yang

doi:10.1007/s40242-015-4309-x

Chemical Research in Chinese Universities ›› 2015, Vol. 31 ›› Issue (1) : 71 -77. DOI: 10.1007/s40242-015-4309-x

Article

Synthesis and biological evaluation of novel saccharin derivatives containing 1,2,3-triazole moiety

Xiaobin Tang ¹^,⁵
, Zhenghui Li ¹^,⁵
, Yonghong Li ³
, Wei Liu ²^,^d
, Peng Yu ¹
, Lixin Li ⁵
, Yu Guo ⁴
, Cheng Yang ⁴^,⁵

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Abstract

A series of novel saccharin derivatives containing 1,2,3-triazole moiety was synthesized in satisfactory yields. The structures of all the compounds were elucidated and confirmed by Fourier transform infrared(FTIR) spectroscopy, ¹H and ¹³C nuclear magnetic resonance(¹H NMR, ¹³C NMR) spectroscopy, and high resolution mass spectrometry(HRMS). The bioassays indicated that most of the title compounds displayed some extent herbicidal activities at 100 μg/mL.

Keywords

Saccharin / 1,2,3-Triazole / Biological activity / Herbicidal

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Xiaobin Tang, Zhenghui Li, Yonghong Li, Wei Liu, Peng Yu, Lixin Li, Yu Guo, Cheng Yang. Synthesis and biological evaluation of novel saccharin derivatives containing 1,2,3-triazole moiety. Chemical Research in Chinese Universities, 2015, 31(1): 71-77 DOI:10.1007/s40242-015-4309-x

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