Synthesis, characterization and application of organic-inorganic hybrid and carbaryl-imprinted capillary monolithic column

Abstract

Organic-inorganic hybrid and carbaryl-imprinted capillary monolith was synthesized via methacrylic acid(MAA) as functional monomer, γ-methacryloxypropyltrimethoxysilane(γ-MAPS) as crosslinker and carbaryl as template molecule in an acetonitrile/dichloromethane mixture(1:4, volume ratio). With the capillary column obtained from this monolith, three carbamates(carbaryl, fenobucarb and metolcarb) were separated effectively by electrochromatography with the k _MIP/k _NIP values of 7.57, 1.27 and 1.64, respectively. In 20 mmol/L phosphate buffer solution (pH=3.5) with 30% (volume fraction) of acetonitrile, carbaryl was separated directly from the three-carbamate mixture (carbaryl, fenobucarb and metolcarb) with an effective 15 cm-length imprinted column.

Keywords

Organic-inorganic hybrid / Carbaryl-imprinted capillary / Monolith / Separate

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