Synthesis and fluorescence properties of coumarin glycosides and triazoylglycosides

Abstract

Four coumarin glycosides(1–4) and four coumarin triazoylglycosides(5–8) were synthesized by phase transfer catalytic glycosylation and copper-catalyzed azide-alkyne cycloaddition(CuAAC) respectively from 4-methyl-7-hydroxyl coumarin(4-methylumbelliferone). The structures were characterized by ¹H NMR, MS or IR. The fluorescent properties of the coumarin glycosides and triazoylglycosides were studied in different solvents and compared to those of 4-methyl-7-hydroxyl coumarin.

Keywords

Coumarin glycoside / Coumarin triazolylglycoside / 4-Methyl-7-hydroxyl coumarin / Fluorescence property

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