Selective solid-phase extraction of aloe emodin from aloe by molecularly imprinted polymers

Abstract

The extraction and separation of aloe emodin were optimized via selective molecularly imprinted solid-phase extraction. Molecularly imprinted polymer was prepared from the functional monomer, methacrylic acid and a mixture of ethanol/dodecanol(90/10, volume ratio) as porogen. It overcomes the common problems of imprinting biological polar compounds and shows high selectivity compared favorably with those of non-imprinted polymer and commercially available C₁₈ and silica cartridges in similar aloe emodin tests. Good linearity was obtained between 0.002 and 2.5 mg/mL (r ²=0.998) with relative standard deviations below 3.3%.

Keywords

Aloe emodin / Molecularly imprinted polymer / Solid-phase extraction / High performance liquid chromatography

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