Synthesis and biological activities of novel anthranilic diamides analogues containing benzo[b]thiophene

Abstract

A series of novel anthranilic diamides analogues containing benzo[b]thiophenyl ring was designed and synthesized. Their structures were characterized by melting points, ¹H nuclear magnetic resonance(¹H NMR) and high-resolution mass spectrometry(HRMS). The bioassay tests indicate that their insecticidal activities were weak to moderate. Antibacterial tests indicate that some of the compounds showed favourable activity in vitro against Physalospora piricola, Alternaria solani, Cercospora arachidicola, Gibberella sanbinetti and Phytophthora infestans at a dosage of 50 mg/L.

Keywords

Anthranilic diamide / Benzo[b]thiophene / Insecticidal activity / Antibacterial activity

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