A Novel Photocatalytic Ring Opening Reaction of Silacyclobutanes with Alkenes
Shixun Guo , Wenjinyi Liu , Pan Wang , Wei Wang , Yongqiang Zhang
Chinese Journal of Chemistry ›› 2025, Vol. 43 ›› Issue (23) : 3281 -3286.
Herein, we wish to report a novel photocatalytic ring opening reaction of silacyclobutanes (SCBs) with alkenes using hexafluoroisopropanol (HFIP) as the promoter. The protocol is mild and green, and is capable of accommodating a wide range of active alkenes, allowing for the facile synthesis of challenging silanols with a tetraorganosilicon stereocenter in good yields in combination with the following hydrolysis. Notably, this strategy could be extended to the reaction with ethynylbenziodoxolone.
Photoredox catalysis / Ring-opening / Silacyclobutanes / Organosilicon compounds / Radical reactions / Synthetic methods
2025 SIOC, CAS, Shanghai, & WILEY-VCH GmbH
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