Divergent Synthesis of 2-Quinolinones and Indolin-3-ones via Mo-Catalyzed Controllable Carbonyl Deoxygenative Coupling and Formal Deoxygenative N—H Insertion Reactions
Jia-Sheng Yao , Xiaoxi Su , Yi-Zhe Yu , Jiang-Bin Wu , Shuanglin Qu , Chun-Xiang Zhuo
Chinese Journal of Chemistry ›› 2025, Vol. 43 ›› Issue (13) : 1538 -1546.
Divergent Synthesis of 2-Quinolinones and Indolin-3-ones via Mo-Catalyzed Controllable Carbonyl Deoxygenative Coupling and Formal Deoxygenative N—H Insertion Reactions
The divergent synthesis of 2-quinolinones and indolin-3-ones through unprecedented Mo-catalyzed controllable carbonyl deoxygenative coupling and formal deoxygenative N—H insertion reactions was reported. By simply changing the molybdenum catalytic conditions, both product categories were produced in generally good yields and with high chemoselectivities from the same starting materials. This strategy was robust, convenient and ready for the rapid construction of diverse product libraries.
Molybdenum catalysis / Divergent synthesis / Deoxygenative functionalization / 2-Quinolinones / Indolin-3-ones / Carbenes / Cyclization / Synthetic methods
2025 SIOC, CAS, Shanghai, & WILEY-VCH GmbH
/
| 〈 |
|
〉 |
PDF
