Epigenomic exploration of disease status of EGFR-mutated non-small cell lung cancer using plasma cell-free DNA hydroxymethylomes

Yong Peng; Jason Karpus; Jyoti D. Patel; Everett E. Vokes; Marina Chiara Garassino; Kirsteen Lugtu; Zhou Zhang; Wei Zhang; Mengjie Chen; Chuan He; Christine M. Bestvina

doi:10.1002/cac2.12606

Cancer Communications ›› 2025, Vol. 45 ›› Issue (01) :51 -55. DOI: 10.1002/cac2.12606

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Epigenomic exploration of disease status of EGFR-mutated non-small cell lung cancer using plasma cell-free DNA hydroxymethylomes

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Yong Peng, Jason Karpus, Jyoti D. Patel, Everett E. Vokes, Marina Chiara Garassino, Kirsteen Lugtu, Zhou Zhang, Wei Zhang, Mengjie Chen, Chuan He, Christine M. Bestvina. Epigenomic exploration of disease status of EGFR-mutated non-small cell lung cancer using plasma cell-free DNA hydroxymethylomes. Cancer Communications, 2025, 45(01): 51-55 DOI:10.1002/cac2.12606

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References

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[1]	Thai AA, Solomon BJ, Sequist LV, Gainor JF, Heist RS. Lung cancer. Lancet. 2021; 398(10299): 535-54.

[2]	Zhang YL, Yuan JQ, Wang KF, Fu XH, Han XR, Threapleton D, et al. The prevalence of EGFR mutation in patients with non-small cell lung cancer: a systematic review and meta-analysis. Oncotarget. 2016; 7(48): 78985-93.

[3]	Beadell AV, Zhang Z, Capuano AW, Bennett DA, He C, Zhang W, et al. Genome-Wide Mapping Implicates 5-Hydroxymethylcytosines in Diabetes Mellitus and Alzheimer’s Disease. J Alzheimers Dis. 2023; 93(3): 1135-51.

[4]	Guler GD, Ning Y, Ku CJ, Phillips T, McCarthy E, Ellison CK, et al. Detection of early stage pancreatic cancer using 5-hydroxymethylcytosine signatures in circulating cell free DNA. Nat Commun. 2020; 11(1): 5270.

[5]	Cao S, Feng H, Yi H, Pan M, Lin L, Zhang YS, et al. Single-cell RNA sequencing reveals the developmental program underlying proximal-distal patterning of the human lung at the embryonic stage. Cell Res. 2023: 1-13.

[6]	Yuan C, Hu H, Kuang M, Chen Z, Tao X, Fang S, et al. Super enhancer associated RAI14 is a new potential biomarker in lung adenocarcinoma. Oncotarget. 2017; 8(62): 105251-61.

[7]	Jiang Z, Zhao J, Zou H, Cai K. CircRNA PTPRM Promotes Non-Small Cell Lung Cancer Progression by Modulating the miR-139-5p/SETD5 Axis. Technol Cancer Res Treat. 2022; 21: 15330338221090090.

[8]	Unsal M, Kara N, Karakus N, Tural S, Elbistan M. Effects of leptin and leptin receptor gene polymorphisms on lung cancer. Tumour Biol. 2014; 35(10): 10231-6.

[9]	Zhou J, Lin Y, Kang X, Liu Z, Zou J, Xu F. Hypoxia-mediated promotion of glucose metabolism in non-small cell lung cancer correlates with activation of the EZH2/FBXL7/PFKFB4 axis. Cell Death Dis. 2023; 14(5): 326.