Fusobacterium is toxic for head and neck squamous cell carcinoma and its presence may determine a better prognosis

Anjali Chander; Jacopo Iacovacci; Aize Pellon; Radhika Kataria; Anita Grigoriadis; John Maher; Cynthia Sears; Gilad Bachrach; Teresa Guerrero Urbano; Mary Lei; Imran Petkar; Anthony Kong; Tony Ng; Ester Orlandi; Nicola Alessandro Iacovelli; Loris De Cecco; Mara Serena Serafini; David Moyes; Tiziana Rancati; Miguel Reis Ferreira

doi:10.1002/cac2.12588

Cancer Communications ›› 2024, Vol. 44 ›› Issue (08) :879 -883. DOI: 10.1002/cac2.12588

LETTER TO THE JOURNAL

Fusobacterium is toxic for head and neck squamous cell carcinoma and its presence may determine a better prognosis

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¹. Centre for Host-Microbiome Interactions, King’s College London, London, UK

². Comprehensive Cancer Centre, King’s College London, London, UK

³. Department of Oncology, Guys and St Thomas NHS Foundation Trust, London, UK

⁴. Data Science Unit, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy

⁵. Medicine Department, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA

⁶. Institute of Biomedical and Oral Research, The Hebrew University-Hadassah School of Dental Medicine, Hadassah Ein Kerem Campus, Jerusalem, Israel

⁷. Dipartimento di scienze Clinico-Chirurgiche, Diagnostiche e Pediatriche, Università degli studi di Pavia, Pavia, Italy

⁸. Radiation Oncology Department, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy

⁹. Department of Medicine,Weill Cornell Medicine, New York, USA

tiziana.rancati@istitutotumori.mi.it

Miguel.ReisFerreira@kcl.ac.uk

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Anjali Chander, Jacopo Iacovacci, Aize Pellon, Radhika Kataria, Anita Grigoriadis, John Maher, Cynthia Sears, Gilad Bachrach, Teresa Guerrero Urbano, Mary Lei, Imran Petkar, Anthony Kong, Tony Ng, Ester Orlandi, Nicola Alessandro Iacovelli, Loris De Cecco, Mara Serena Serafini, David Moyes, Tiziana Rancati, Miguel Reis Ferreira. Fusobacterium is toxic for head and neck squamous cell carcinoma and its presence may determine a better prognosis. Cancer Communications, 2024, 44(08): 879-883 DOI:10.1002/cac2.12588

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[2]	Reis FerreiraM, PastoA, NgT, PatelV, Guerrero Urbano T, SearsC, et al. The microbiota and radiotherapy for head and neck cancer: what should clinical oncologists know? Cancer Treat Rev. 2022: 109:102442.

[3]	CaselliE, FabbriC, D’AccoltiM, SoffrittiI, BassiC, MazzacaneS, et al. Defining the oral microbiome by whole-genome sequencing and resistome analysis: the complexity of the healthy picture. BMC Microbiol. 2020; 20(1): 120.

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