Inter-fiber spacer-aided rawhide drying for skin-like and eco-friendly wearable platform of e-skin

Haoliang Pu , Hanzhong Xiao , Yujia Wang , Xin Huang , Bi Shi

Collagen and Leather ›› 2026, Vol. 8 ›› Issue (1) : 8

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Collagen and Leather ›› 2026, Vol. 8 ›› Issue (1) :8 DOI: 10.1186/s42825-025-00233-6
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Inter-fiber spacer-aided rawhide drying for skin-like and eco-friendly wearable platform of e-skin
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Abstract

The next-generation on-skin devices are expected to provide identical textural characteristics to skin for accomplishing comfortable long-term wearability. Cattle hide is mainly consisted of type I collagen, which is therefore an ideal collagenous-matrix platform for developing skin-like on-skin devices. However, the raw cattle hide has a high water content that leads to poor wearability. Herein, we developed the skin-like wearable (SW) platform via a brand-new inter-fiber spacer-aided (IFS-aided) drying of cattle hide, where an amphiphilic nonionic surfactant that was capable of thoroughly infiltrating into the 3D hierarchical network of collagen fibers (CFs) was employed to work as the inter-fiber spacer to avoid the sticking of CFs during drying. Moreover, the inter-fiber spacer was easily eluted after drying for obtaining the collagenous matrix with highly dispersed fiber structure. The as-developed SW-platform exhibited ideal wearability by exhibiting full-protein nature, outstanding softness (6.808 mm), exceptional water-vapor permeability (5950 g·m-2·d-1) and high thermal stability. The hierarchical fiber structure with sufficient inter-fiber space endowed the SW-platform with reversible cross-scale deformations of CFs at both the nanoscale and microscale, which demonstrated its promising application in developing the skin-like and eco-friendly e-skins with outstanding sensing capability and flexible display function.

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Keywords

Inter-fiber spacer / Aided drying / Fiber sticking / Skin-like platforms / E-skins

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Haoliang Pu, Hanzhong Xiao, Yujia Wang, Xin Huang, Bi Shi. Inter-fiber spacer-aided rawhide drying for skin-like and eco-friendly wearable platform of e-skin. Collagen and Leather, 2026, 8(1): 8 DOI:10.1186/s42825-025-00233-6

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References

[1]

Chen F, Huang Q, Zheng Z. Permeable conductors for wearable and on-skin electronics. Small Struct, 2022, 3(1): 2100135

[2]

Yang J, Mun J, Kwon S, Park S, Bao Z, Park S. Electronic skin: recent progress and future prospects for skin-attachable devices for health monitoring, robotics, and prosthetics. Adv Mater, 2019, 31(48): 1904765

[3]

Liu J, Fan X, Astruc D, Gu H. Robust conductive skin hydrogel e-skin constructed by top–down strategy for motion-monitoring. Collagen Leather, 2023, 5(1): 17

[4]

Hammock ML, Chortos A, Tee BCK, Tok JB, Bao Z. 25th anniversary article: the evolution of electronic skin (E-Skin): A brief history, design considerations, and recent progress. Adv Mater, 2013, 25(42): 5997-6037

[5]

Oh JY, Rondeau-Gagné S, Chiu YC, Chortos A, Lissel F, Wang GJN, et al. . Intrinsically stretchable and healable semiconducting polymer for organic transistors. Nature, 2016, 539(7629): 411-5

[6]

Ma Z, Huang Q, Xu Q, Zhuang Q, Zhao X, Yang Y, et al. . Permeable superelastic liquid-metal fibre mat enables biocompatible and monolithic stretchable electronics. Nat Mater, 2021, 20(6): 859-68

[7]

Yan Z, Xiong J, Wang B, Gao M, Yin G, Hu T, et al. . Recent advances in breathable electronics. Nano Res, 2023, 16(3): 4130-4142

[8]

Han Y, Hu J, Sun G. Recent advances in skin collagen: functionality and non-medical applications. J Leather Sci Eng, 2021, 3(1): 4

[9]

Shoulders D, Raines T. Collagen structure and stability. Annu Rev Biochem, 2009, 78(1): 929-958

[10]

Zheng L, Tseomashko N, Voronova A, Vasil’kov A, Hu X, Wang X, et al. . Recent advances of collagen composite biomaterials for biomedical engineering: antibacterial functionalization and 3D-printed architecturalization. Collagen Leather, 2024, 6(1): 22

[11]

Feng B, Yang H, Zhu M, Li J, Chang H, Leung P, et al. . Collagen-based biomaterials in organoid technology for reproductive medicine: composition, characteristics, and applications. Collagen Leather, 2023, 5(1): 35

[12]

Sallent I, Leon L, Aguirre-Álvarez G, et al. . Assessing the potential of caprine collagen type I in the development of medical devices. Biomacromolecules, 2025, 26(10): 6418-6429

[13]

Liu H, Yang R, Zhao S, Zhou F, Liu Y, Zhou Z, et al. Collagen scaffolds derived from bovine skin loaded with MSC optimized M1 macrophages remodeling and chronic diabetic wounds healing. Bioen Trans Med. 2023;8(3):e10467.

[14]

Gómez-Guillén M, Giménez B, López-Caballero M, Montero M, Nair BU. Functional and bioactive properties of collagen and gelatin from alternative sources: A review.. Food Hydrocolloid, 2011, 25(8): 1813-1827

[15]

Shirai T, Hattori S, Sakaguchi M, Inouye S, Kimura A, Ebihara T, et al. . The complete cDNA coding sequence for the bovine proα2 (I) chain of type I procollagen. Matrix Biol, 1998, 17((1)): 85-88

[16]

Cao Y, Zheng W, Hao B, Cui Y, Huang X, Shi B, et al. . Structural engineering‐enabled joule heating effect cooperated with capillary effect toward fast spreading of droplets for high‐flux separation of viscous emulsion. Small Methods, 2023, 7(11): 2300513

[17]

Ke L, Wang Y, Ye X, Luo W, Huang X, Shi B. Collagen-based breathable, humidity-ultrastable and degradable on-skin device. J Mater Chem C, 2019, 7(9): 2548-56

[18]

Wei Y, Hao B, Wang Y, Wang Y, Xiao H, Li L, Huang X, Shi B. Tannery solid waste-derived cross-scale deformable piezoresistive sensors for monitoring human body motions. J Mater Chem C, 2022, 10(21): 8199-205

[19]

Zheng W, Hao B, Huang X, Shi B. From leather to the next-generation skin-friendly e-skin. Collagen Leather. 2025;7(1):1–6.

[20]

Fathima NN, Dhathathreyan A. Effect of surfactants on the thermal, conformational and rheological properties of collagen. Int J Biol Macromol, 2009, 45(3): 274-8

[21]

Maldonado F, Almela M, Otero A, et al. . The binding of anionic and nonionic surfactants to collagen through the hydrophobic effect. J Protein Chem, 1991, 10(2): 189-92

[22]

Gopalakrishnan D, Balachandar V, Kumbharkhane AC, et al. . Dielectric relaxation studies of collagen–surfactant complexes in aqueous buffer solution. Int J Biol Macromol, 2019, 138: 215-23

[23]

Luo X, Huo Q, Liu X, Chi Z, Ying L. Effect of hydrophilic or hydrophobic interactions on the self-assembly behavior and micro-morphology of a collagen mimetic peptide. J Leather Sci Eng, 2021, 3(1): 11

[24]

Xiao H, Wang Y, Hao B, Cao Y, Cui Y, Huang X, Shi B. Collagen fiber-based advanced separation materials: recent developments and future perspectives. Adv Mater, 2022, 34(46): 2107891

[25]

Das S, Mondal S, Ghosh S. Physicochemical studies on the micellization of cationic, anionic, and nonionic surfactants in water–polar organic solvent mixtures. J Chem Eng Data, 2013, 58(9): 2586-95

[26]

Kronberg B, Holmberg K, Lindman B. Surface chemistry of surfactants and polymers. Wiley; 2014.

[27]

Mezzenga R, Seddon JM, Drummond CJ, Boyd BJ, Schröder-Turk GE, Sagalowicz L. Nature‐inspired design and application of lipidic lyotropic liquid crystals. Adv Mater, 2019, 31(35): 1900818

[28]

Dong J, Tang X, Peng Y, Fan C, Li L, Zhang C, et al. . Highly permeable and ultrastretchable E-textiles with EGaIn-superlyophilicity for on-skin health monitoring, joule heating, and electromagnetic shielding. Nano Energy, 2023, 108: 108194

[29]

Nam S, Park C, Sunwoo SH, Kim M, Lee H, Lee M, Kim DH. Soft conductive nanocomposites for recording biosignals on skin. Soft Sci. 2023;3(3):28.

[30]

Oh J, Jang SG, Moon S, Kim J, Park HK, Kim HS, et al. . Air-permeable waterproofing electrocardiogram patch to monitor full‐day activities for multiple days. Adv Healthc Mater, 2022, 11(12): 2102703

[31]

Chen F, Zhuang Q, Ding Y, Zhang C, Song X, Chen Z, et al. . Wet-adaptive electronic skin. Adv Mater, 2023, 35(49): 2305630

Funding

Joint Funds of the National Natural Science Foundation of China(No. U24A20545)

National Natural Science Foundation of China(No. 2217081161)

Program of Sichuan University Featured Research Groups in Engineering Disciplines(Program of Sichuan University Featured Research Groups in Engineering Disciplines)

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