2025-04-30 2025, Volume 20 Issue 2

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  • research-article
    Liqi Cao , Tingting Chen , Chen Liu , Yueru Li , Xiaoqiu Liu , Xiajing Xu , Yingni Pan
    2025, 20(2): 49-64. https://doi.org/

    Ultra-performance liquid chromatography-mass spectrometry (UPLC-MS) technology was employed to analyze the chemical composition of three Clematidis Radix et Rhizoma sourced from different origins. Common characteristic components were identified through comprehensive literature review and the integration of fragment ion data. A rheumatoid arthritis (AA) model was induced in Sprague-Dawley (SD) rats using Freund’s complete adjuvant, and simultaneous administration of extracts from the three original plants of Clematidis Radix et Rhizoma, along with different doses of magnoflorine, was conducted to evaluate differences in therapeutic efficacy. A common characteristic component was identified, magnoflorine, present in Clematis chinensis Osbeck. Clematis hexapetala Pall., and Clematis manshurica Rupr. Extracts from all three original plants, as well as each dose group of the Rhizomas of Clematis chinensis Osbeck. Clematis hexapetala Pall., Clematis manshurica Rupr., and magnoflorine, demonstrated efficacy in alleviating rheumatoid arthritis symptoms by enhancing cellular infiltration, reducing vascular opacification, and lowering serum levels of inflammatory factors. Magnoflorine has the potential to be used as a quality marker for the three original plants of Clematidis Radix et Rhizoma. Additionally, both the three original plants and magnoflorine exhibit therapeutic potential for rheumatoid arthritis, which provides a solid theoretical and experimental basis for the establishment of more scientifically grounded quality standards of Clematidis Radix et Rhizoma and promotes the rational utilization of medicinal resources.

  • research-article
    Yunpeng Yang , Ruiqi Ma , Yuzheng Xiang , Yu Wang , Rui Liu , Ying Li , Yu Chen
    2025, 20(2): 65-76. https://doi.org/

    Scutellaria baicalensis (S. baicalensis) is a heat-clearing and moisture-drying medicine, which is used to treat diseases such as warm fever, upper respiratory tract infection, lung heat cough, moist heat jaundice, pneumonia, dysentery, hemoptysis, red eyes, restless fetus, hypertension, abscess, swelling and boils. In recent years, with the in-depth study of its chemical composition and pharmacological activity, it was found that the clinical antibacterial activity of S. baicalensis was significant, and it did not produce drug resistance. The chemical constituents and pharmacological effects of S. baicalensis were reviewed in this paper. This review can provide reference for further development and utilization of medicinal value of S. baicalensis.

  • research-article
    Shuxing Tian , Lan Zou , Yue Yang , Qiaoyan Yang , Fayun Zi , Pan Zhang
    2025, 20(2): 77-89. https://doi.org/

    Crotalaria ferruginea Graham ex Benth. is a commonly used herb among ethnic minorities. Its whole plant is used as medicine for conditions such as heatstroke, tinnitus, hearing loss, phlegm heat cough, gum swelling and pain, lower back and knee pain, vaginal discharge and infantile malnutrition. Modern pharmaceutical research has found that Crotalaria ferruginea Graham ex Benth. mainly contains flavonoids, steroids, organic acids and terpenes, which have antibacterial, free radical scavenging, anti- inflammatory and other effects. Quality control mainly focuses on characteristics, identification, content determination, etc. This article summarizes the recent research progress on the chemical composition, pharmacological effects, quality control and extraction process of Crotalaria ferruginea Graham ex Benth. on the basis of existing Crotalaria ferruginea Graham ex Benth. research reports.

  • research-article
    Jiankun Jin , Rui Liu , Ruiqi Ma , Yuzheng Xiang , Yibo Wang , Meng Zhang , Yu Chen
    2025, 20(2): 90-98. https://doi.org/

    Plant diseases affect the cultivation of Chinese herbal medicines, while traditional chemical pesticides have many drawbacks such as environmental pollution, health risks and disruption of ecological balance. Microbiocontrol has gradually appeared in public view, and its application has become increasingly extensive. This paper reviews the disease-causing species of medicinal plants, including fungal, bacterial, nematode, viral and parasitic pests, and reviews the diseases caused by microorganisms in traditional Chinese medicine planting and their biological control by consulting Sciencedirect databases and Web of Science databases. 4667 related articles were found, of which 552 were related to microbiocontrol technology and cultivation of traditional Chinese medicines. This review provides a reference for the green planting technology of traditional Chinese medicine.